I don't even want my browser to have a 'local file context', is there a way to switch such behavior off entirely until explicit permission is given? All these extra bells and whistles added to browsers to allow websites to pretend they're 'native apps' should require a very large switch to be thrown from 'safe' to 'unsafe' whenever an application requests such a thing. And what a pdf reader has to do with javascript…
Run the browser in a container or in a sandboxed environment (kindof like chroot, but note that chroot itself should not be used for security purposes). There may be docker containers with just firefox, if not it's easy to create one. Or use vmware, though that is much more heavyweight than sandboxing or containers.
Sandboxie has gotten very good over the years. You can sandbox programs that even run with admin privileges.
edit: Don't think sandboxie can load drivers.