41–50 of 52 posts
You'll delay as many of the diseases of aging as much as you can by doing those things. Packaging their effects in a pill would make you the richest person in history.
The fountain of youth is regular strength training, cardio, quality sleep, good relationships, indulging your curiosity and learning new things, and a diet high in protein (for the exercise) and plenty of plant based whole foods like leafy green vegetables. You'll delay as many of the diseases of aging as much as you can by doing those things. Packaging their effects in a pill would make you the richest person in his…
Earlier quoted context omitted.
Having children or grandchildren is even more of a reason to be interested in research that prevents the diseases of aging (longevity). When you get the diseases of aging that precede death, like Alzheimer’s or cancer or heart disease or just simply becoming frail, your children and grandchildren suffer greatly. What is narcissistic about not wanting your children and grandchildren to watch you suffer one or more of…
The history of extending human life through sanitation, disease prevention (vaccines and antibiotics), and treatment for chronic conditions has so far led to even worse conditions brought on by age. Centuries ago almost no one lived long enough to die from heart disease, cancer, or dementia. Now those are common, diseases of old age, imposing tremendous costs. I don’t propose going back to 35 year lifespans or some k…
This is false. The life expectancy one you reached puberty was very similar to the current one. The 35 years lifespans were due to insane infant mortality. Modern medicine has been able to avoid the death of children but it hasn't being able to extend the duration of your healthy life other than from the statistical point of view.
Earlier quoted context omitted.
The history of extending human life through sanitation, disease prevention (vaccines and antibiotics), and treatment for chronic conditions has so far led to even worse conditions brought on by age. Centuries ago almost no one lived long enough to die from heart disease, cancer, or dementia. Now those are common, diseases of old age, imposing tremendous costs. I don’t propose going back to 35 year lifespans or some k…
>Centuries ago almost no one lived long enough to die from heart disease, cancer, or dementia. Now those are common, diseases of old age, imposing tremendous costs. I don’t propose going back to 35 year lifespans This is false. The life expectancy one you reached puberty was very similar to the current one. The 35 years lifespans were due to insane infant mortality. Modern medicine has been able to avoid the death of…
Earlier quoted context omitted.
The history of extending human life through sanitation, disease prevention (vaccines and antibiotics), and treatment for chronic conditions has so far led to even worse conditions brought on by age. Centuries ago almost no one lived long enough to die from heart disease, cancer, or dementia. Now those are common, diseases of old age, imposing tremendous costs. I don’t propose going back to 35 year lifespans or some k…
> Centuries ago almost no one lived long enough to die from heart disease, cancer, or dementia. Right, they were dying of infections, starvation, childbirth and cholera, appendicitis and anthrax, typhoid and typhus, polio and tetanus. Are you saying that those were better?
The NIH Interventions Testing Program has identified 6 compounds that significantly extend HEALTHY life (in model animals). Some of these compounds have been tested in multiple model animals and the effect is conserved across all of them. Human trials are expensive and obviously take multiple decades, so you’ll be dead before to see that data. The compounds so far are: rapamycin, acarbose, 17-alpha-estradiol, canagli…
> meclizine The anti-nausea drug?
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You will have stopped existing way before your body reaches 60. What I mean by this is that current-you and 60-year-old you will be so different from each other that they could be different individuals entirely. You will likely still share some atoms by mere chance, but most of your 60yo body will be made of different atoms. 60yo’s mind will have many memories and experiences in common with you, but also a bunch of d…
I’ve had a surprisingly consistent sense of self. At least as far as I can remember. My personality, sense of fairness, hopes dreams, interests. All consistent. I’ll certainly be the same person at 60. Hopefully wiser and handsomer.
I think most people do feel a strong sense of self, and that they feel it is extremely consistent. I am having trouble picturing some who isn’t like that in my head, actually. Perhaps someone who’s barely conscious, or a baby.
I also think that despite that feeling, change is unavoidable for everyone and uncomfortable for a lot of us. Some will go to extremes like changing their own memories in order to avoid admitting that they changed.
Among the most promising anti-aging drugs is metformin. Type 2 diabetics on metformin live 15% longer than non-diabetics. This is remarkable considering how big a health disadvantage diabetes itself is. Metformin seems to mimic fasting somehow, by interfering with mitochondrial function. For more information I refer you to David Sinclair's numerous discussions on this topic. He takes 1 gram of metformin per day with…
At the begging I had nausea issues with it but eventually switch to longterm release and I’m the side effects went away unless I don’t eat.
It truly helps with controlling the appetite and brought my diabetes under control. I don’t feel any younger but I hope the studies/discussion mentioned are truly legit.
The fountain of youth is regular strength training, cardio, quality sleep, good relationships, indulging your curiosity and learning new things, and a diet high in protein (for the exercise) and plenty of plant based whole foods like leafy green vegetables. You'll delay as many of the diseases of aging as much as you can by doing those things. Packaging their effects in a pill would make you the richest person in his…