131–140 of 633 posts
I started doing research on cameras around 2012 and have been obsessed every since. The company behind this code failed unfortunately but I've kept poking at it and finding more people interested in it, even as my day job is more about cloud infrastructure. Companies like Zippin which have carved out a niche in the cashierless space really impress me.
There's this whole world of rules that accountants follow to properly record revenue. These rules are different for physical products, subscriptions, contracts, and even rules for what to do when you bundle these things together. And yet, the only two options for companies to crunch all this data is to use an Oracle product or Excel. (Or get the eng team to write SQL queries, to try and produce a correct result for a topic they don't have a background in!)
To do this, we're really leaning into databases like Clickhouse and DuckDB - taking raw data and very quickly summarizing them into journal entries that you can post during the month. Also using kinesis to let users stream in financial data in realtime, so we can then process that data in batch. (Kinesis -> S3 -> Lambda -> DB). In doing this, have also been writing low-level C and Go code to quickly iterate over a stream of transactions and accumulate results.
My sister works as a veterinarian and is experiencing some serious burnout from her current practice (a subsidiary of a larger corporation). I guess it's pretty common practice for corporations or private equity to snatch up smaller independent practices and then run them like a sweat shop. Her current CEO's resume is a list of Starbucks, Walmart, and a few other corporate roles that are totally unrelated to the medi…
Investors can only invest in scalable, replicable businesses. Veterinary practices are intensely personal, often specialize in different species and breeds, and can develop unique experimental treatments. The cost of labor is ridiculously cheap (people become Vet Tech's for love, not money), and buildings need not be in commercial centers, so capital costs are minimal.
Honestly, veterinarians are really in the best possible profession for maintaining independent practices. If they can't resist investor takeover, who can?
A little while ago, a patent for high throughput DNA synthesis using silicon chips went off-patent, so I have been learning analog IC chip design to build an open source high-throughput DNA synthesis chip. If it works, and I sold them at cost, it would reduce the cost of oligo pool synthesis by ~100x and possibly gene synthesis by 10x. For about 8-9 years now my goal has been to build a cell from scratch for less tha…
For anyone interested, found following blog post on OP’s website, which is linked to from their HN profile: _____ How to make DNA synthesis affordable https://keonigandall.com/posts/affordable_dna_2.html
I encourage him to continue explore new ways of making DNA, but understanding the market is very different from building off an expired patent.
Earlier quoted context omitted.
Your name, password, and the names and addresses and phone numbers and emails of all your family members already exist and are being used. So, by your logic, you have no reason to share them to everyone? The logic doesn’t hold up. You can make the same argument for anything. It makes sense to think about the dangers, not pretend that bad logic is an excuse to do anything you want.
No, actually your first sentence's logic doesn't hold up as it isn't a fair comparison at all. You can already order custom oligos and synthesized genes for relatively cheap. The chip idea would just reduce the cost more.
My sister works as a veterinarian and is experiencing some serious burnout from her current practice (a subsidiary of a larger corporation). I guess it's pretty common practice for corporations or private equity to snatch up smaller independent practices and then run them like a sweat shop. Her current CEO's resume is a list of Starbucks, Walmart, and a few other corporate roles that are totally unrelated to the medi…
What's wrong with opening your own practice? Investors can only invest in scalable, replicable businesses. Veterinary practices are intensely personal, often specialize in different species and breeds, and can develop unique experimental treatments. The cost of labor is ridiculously cheap (people become Vet Tech's for love, not money), and buildings need not be in commercial centers, so capital costs are minimal. Hon…
This is absolutely not true and it's a big issue in the field currently (my wife is a Veterinarian). This kind of thinking is also what is causing a lot of mental health issues in the field.
I’m working on making body doubling a more main stream approach to accomplishing everyday tasks. Body doubling is known within the ADHD community and entails performing a task in the presence of another. More details here: https://www.healthline.com/health/adhd/body-double-adhd It helps to engage motivation by using another person as the proxy. I wrote a bit about how I think it works here: https://doubleapp.xyz/blog…
Neat! I look forward to seeing more - For a long time I found myself saying absurd things like "i work better in distracting environments" or "It's easier to have a clean house with roomates to clutter it up". What really was happening was that I respond well to body doubling. (Never diagnosed with any sort of executive functioning disorder, but I suspect that's more because I never went and got diagnosed than me lac…
I’m collaborating on an attempt to shift the responsibility for XSS from the developers and towards the browser. The current stage focuses on getting the use case "insert HTML but without any scripts" right.
There’s a public specification and prototype implementations in Firefox and Chrome. You can play with it here https://sanitizer-api.dev/
We think that we’ve made the best of many different tradeoffs, but we’re also keen to hear wide feedback.
I'm going back to basics and learning to write a compiler in the dumbest way possible. I'm starting with a basic assignment (a = 3) and reverse engineering what it would take to turn that into a working executable. Then I'll add more features, lather, rinse and repeat. I'm hoping to eventually turn it into a series of blog posts so everyone can see just how little I remember from college.