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nik_s

HN member
Joined
Thu, Sep 05, 2019, 8:17 PM UTC
HN karma
210
Public activity
30 items

About nik_s

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Recent public activity

  1. comment
    Comment #38420145

    The mitochondria in many cancer cell behave abberantly. For example, in many cases, they can start promoting glycolysis, in process known as the Warburg effect. They're also involv…

  2. comment
    Comment #38413953

    I think this is a very cynical take. Patients with gastric cancer are often in a dire situation: many of them have had their stomach removed and have generally significant difficul…

  3. comment
    Comment #38413823

    I work in drug discovery (including in oncological indications), so it's always great to see new research with early, promising results! To summarize the paper: some gastric cancer…

  4. comment
    Comment #35914345

    While I agree with the general sentiment of your message, there are quite a few meta-analyses on pubmed on the long-term safety and efficacy of gastric bypass surgery. They mostly …

  5. comment
    Comment #32928348

    It can do both - I've edited my original post to show the translation task.

  6. comment
    Comment #32928207

    I just tested the model [1] using an RTX3090, trying to translate a french text I found here [2]. Some observations: - The full translation of the 6:22 minute video takes about 22 …

  7. comment
    Comment #32662865

    This [1] study was pretty thorough on different fasting lengths. They tested 1422 patients for fasting lengths between 4 and 21 days, with a maximum calorie consumption of 200-250k…

  8. comment
    Comment #32662635

    You can order these drugs in bulk from chemical vendors for research purposes (i.e. non-human use). Chemscene, to name just one, sells Rapamacyn at 1440 USD for 5g. EDIT: I clearly…

  9. comment
    Comment #30073080

    Regarding the biology: - One of the strategies in drug development is to find a protein that is more present in people who have a disease versus those who don't (called "overexpres…

  10. comment
    Comment #29875538

    You can also say that blockchains have mechanisms that prevent a government from coercing third parties from handing over your NFTs to someone else. I'll agree that the analogy was…

  11. comment
    Comment #29875191

    I'm not sure I agree with your explanation. Most NFTs are like a title to a house. Like a title to a house, you can: 1. Prove you own it; 2. Sell it to someone. Unlike the title to…

  12. comment
    Comment #26648255

    I worked in the same co-working space as Wietse, Aline and Koen, the three co-founders of Citizenlab, when they were launching their service. They're a super competent team with a …

  13. comment
    Comment #25832021

    A minor point about the podcast: Alex Hern misunderstood the process that Craig Wright, the self-processed founder of bitcoin (Satoshi Nakamoto), needed to go through to prove that…

  14. comment
    Comment #25789683

    The author implies that the recent growth in tether's market cap is an indication of an incoming exit scam. A cursory glance at Coinbase's USDC's market cap [1] shows that it too i…

  15. comment
    Comment #24602076

    Incredibly interesting research: hopefully this pans out in human studies too. If I understand correctly, in order to achieve this: 1. a nanotube is created that contains a chemica…

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  18. comment
    Comment #24515157

    I totally understand the sentiment, and generally, when I do solo projects or projects with small teams, I also prefer light frameworks. In my experience, frameworks like Django an…

  19. comment
    Comment #24515004

    Congrats on the release! Actix is super exciting, and it's great to see how the community stepped up to maintain this amazing project. Is there any effort to bring a Rails/Django l…

  20. comment
    Comment #23498021

    On top of that, the author uses aiopg rather than asyncpg[1] for the async database operations, even though asyncpg is (allegedly) a whole lot faster. 1. https://github.com/MagicSt…

  21. comment
    Comment #23012781

    I'm the CTO at a data science company, and this has been my experience too. I've been lucky enough to have quite a few engineers go from zero practical experience to being able to …

  22. comment
    Comment #22823029

    Very nice! For those who are just skimming the link, this is actually a demonstration of the capabilities of a python package that is available on github [1]. If I understand corre…

  23. comment
    Comment #22434460

    Thank you - I came to the same conclusion while still editing my post - I think my edit and your post coincided. I clarified this edit in my original post.

  24. comment
    Comment #22434309

    I think you're referring specifically to the "political and cultural pressure in China" part of my original post. I was basing this on reporting from the New York Times [1] of the …

  25. comment
    Comment #22434050

    If my original post gave off the impression of being conspiracy-theory-driven, I want to apologize, because that wasn't the intent. My original post aimed at clarifying that death …