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Wink Health: Making Five Guys Less Fattening

winkhealth.com

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Re: Wink Health: Making Five Guys Less Fattening

#5

How did you prepare the kale? The graph says "Time (s)", but those can't be seconds. What's up? So you did a dozen pinpricks to measure glucose? Does that start to get bothersome?

I just ate the kale raw from a box. The brand was Taylor Farms, i.e.

http://www.taylorfarms.com/products/organic-salads/baby-kale...

This is an unreasonable amount of kale :-). I'm going to need to figure out a better meal:kale ratio or use a different vegetable side.

Actually, you're right. They're minutes. I started sampling my blood glucose when I started eating. Let me go ahead and add annotations to some of those data points, especially the data points that correspond to the end of the meal.

Re: Wink Health: Making Five Guys Less Fattening

#6
post #5

How did you prepare the kale? The graph says "Time (s)", but those can't be seconds. What's up? So you did a dozen pinpricks to measure glucose? Does that start to get bothersome?

I just ate the kale raw from a box. The brand was Taylor Farms, i.e. http://www.taylorfarms.com/products/organic-salads/baby-kale... This is an unreasonable amount of kale :-). I'm going to need to figure out a better meal:kale ratio or use a different vegetable side. Actually, you're right. They're minutes. I started sampling my blood glucose when I started eating. Let me go ahead and add annotations to some of thos…

Wilted kale and spinach both lose a crazy amount of volume. I wonder how that would affect the experiment. It would be much easier to eat a large volume. Just fry in a pan with a bit of salt and oil.

Also, does caffeine in soda (so often paired with this meal) speed digestion enough to make blood sugar spike? I always assumed that caffeine increases your metabolism, but I didn't consider that speeding digestion is worse for blood sugar.

Re: Wink Health: Making Five Guys Less Fattening

#7

How did you prepare the kale? The graph says "Time (s)", but those can't be seconds. What's up? So you did a dozen pinpricks to measure glucose? Does that start to get bothersome?

Re: the experiment being bothersome... yes, it was!

I sampled my blood glucose every ten minutes, which might have been unnecessarily frequent. Having to interrupt myself every ten minutes to do a pinprick prevented me from doing anything that required concentration. I basically found myself watching YouTube videos for two hours.

I've heard of people doing continuous blood glucose monitoring, but this may be a bit heavyweight. I really only have to do this a few times for a few different meals to get an idea of what is needed by my body.

Re: Wink Health: Making Five Guys Less Fattening

#8
post #5

Earlier quoted context omitted.

I just ate the kale raw from a box. The brand was Taylor Farms, i.e. http://www.taylorfarms.com/products/organic-salads/baby-kale... This is an unreasonable amount of kale :-). I'm going to need to figure out a better meal:kale ratio or use a different vegetable side. Actually, you're right. They're minutes. I started sampling my blood glucose when I started eating. Let me go ahead and add annotations to some of thos…

Wilted kale and spinach both lose a crazy amount of volume. I wonder how that would affect the experiment. It would be much easier to eat a large volume. Just fry in a pan with a bit of salt and oil. Also, does caffeine in soda (so often paired with this meal) speed digestion enough to make blood sugar spike? I always assumed that caffeine increases your metabolism, but I didn't consider that speeding digestion is wo…

The experiment with sautéed kale and spinach is worth a try. If it is made too soft though, it may not slow down digestion much.

I hypothesize that a mix of coarse vegetables, for example, one that includes broccoli, kale, red cabbage, and cauliflower, would slow down the digestion rate even more than 10 oz of kale. Replacing the kale with dino kale would make this mix even better.

I didn't drink soda with the meal, simply because I don't normally drink soda with this meal, but an experiment with a caffeinated beverage would be easy enough to do.

One of the things we're working on is quantifying how different things, such as caffeine intake, affect your metabolic rate. This is the subject of an upcoming blog post.

Re: Wink Health: Making Five Guys Less Fattening

#9
This is at best incomplete, armchair science, and at worst dangerous. The founders are all entrepreneurs / engineers, which is to say they don't have a medical degree or any expertise in biochemistry, so their argument is on the whole just skewed to deliver the argument that suits them - which is, "can I stuff enough kale in my mouth to slow down the release of insulin, and therefore reduce blood glucose".

Here's a few other things that reducing insulin does:

1. Decreases amino acid uptake

2. Decreases potassium uptake

3. Reduces brain insulin signaling, reducing control of energy homeostatis.

Insulin, in isolation, isn't bad. It helps increase muscle and improves cognition. What is bad is the way it fluctuates in the body and the ability for the body to regulate glucose and insulin efficiently. It's perfectly normal for a healthy individual to have a blood glucose reading of 140-150 after a carb-heavy meal. The key is how long does it take for their glucose to reduce back down to healthy levels (70-100). If it's 2 hours or less, you're fine. If it's longer than that, now you've got issues. Even then, acute blood glucose levels can vary wildly from individual to individual, particularly if they're on a ketogenic diet low in carbs, and that may report actually higher than normal (because you're constantly looking to the body to make glucose instead of food, so basal levels must remain higher).

Fear not glucose and insulin. Fear insulin resistance and glucose intolerance.

So getting back to the title of the article, the more practical way of making Five Guys less fattening is not to surround a burger in a basket of kale in your stomach, but to either (A) not eat the burger in the first place or (B) improve your insulin resistance/glucose tolerance. All that the article's experiment would do (in reality) is reduce your desire to eat a burger because your stomach is filled with kale - slow or fast, your body still had to break down and consume that burger. But if you exercise, eat right most of the time, and keep your vices in moderation, your improved lipid profile, fasting insulin, fasting glucose (and A1C), and insulin resistance/glucose tolerance will allow you to more efficiently process that burger so it is not as taxing on your body as it would be if you were not as healthy.

Re: Wink Health: Making Five Guys Less Fattening

#10
post #5

How did you prepare the kale? The graph says "Time (s)", but those can't be seconds. What's up? So you did a dozen pinpricks to measure glucose? Does that start to get bothersome?

I just ate the kale raw from a box. The brand was Taylor Farms, i.e. http://www.taylorfarms.com/products/organic-salads/baby-kale... This is an unreasonable amount of kale :-). I'm going to need to figure out a better meal:kale ratio or use a different vegetable side. Actually, you're right. They're minutes. I started sampling my blood glucose when I started eating. Let me go ahead and add annotations to some of thos…

Have you tried using an equivalent amount of water and/or fiber supplements as a control? It seems reasonable to conclude that eating additional food would cause you to feel satiated for longer.
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