I've been looking into this seriously for the past week or two. People say uWSGI is one of the best. But then it's only for Unix (no, I don't want to use Cygwin). What about FAPWS3? It seems to be doing well in scenarios which are event-based. Not my cup of tea. Am looking for, for a normal web application. GUnicorn? Oh no .. again, unix flavored! mod_wsgi : seems to work well with Apache. But I doth not touch that bulky guy called Apache! nor do I have enough expertise to tweak it well enough to perform to my needs. CherryPy? Not much noise around it, in the Web at least. Your thoughts? Experiences?