Live data from Hacker News

A $650M Donation for Psychiatric Research

nytimes.com

1–10 of 39 posts

Re: A $650M Donation for Psychiatric Research

#2
This is a huge donation for the Broad and probably equals all their previous fundraising. I think a lot will ask if it's too much to one institute or too little to solve the problem, but overall I'm very excited. Biology is changing very fast right now, and it's probably the right time for a big new push. Psychiatric disease and brain research is the next big frontier and private funding like this allows places to take risks they otherwise couldn't on grants. The Broad Institute is the best genomics institute by far, albeit a little light on the clinical side. The money will not be wasted on anything hokey. All that said though, there is a large chance that it still won't be enough to solve a very tough set of problems.

Re: A $650M Donation for Psychiatric Research

#3
post #2

This is a huge donation for the Broad and probably equals all their previous fundraising. I think a lot will ask if it's too much to one institute or too little to solve the problem, but overall I'm very excited. Biology is changing very fast right now, and it's probably the right time for a big new push. Psychiatric disease and brain research is the next big frontier and private funding like this allows places to ta…

>All that said though, there is a large chance that it still won't be enough to solve a very tough set of problems.

I agree, but hope that it is enough to move research along to the point where the pharma industry will see something worth researching and developing.

Re: A $650M Donation for Psychiatric Research

#5
post #2

This is a huge donation for the Broad and probably equals all their previous fundraising. I think a lot will ask if it's too much to one institute or too little to solve the problem, but overall I'm very excited. Biology is changing very fast right now, and it's probably the right time for a big new push. Psychiatric disease and brain research is the next big frontier and private funding like this allows places to ta…

I really appreciate that the Broad keeps a lot of attention on basic (or at least, pre-clinical) research. That kind of work is critical to making big discoveries but it's harder to defend for funding in a world where we want to put drugs on shelves. I still want to see drugs on shelves, but starting at the clinic isn't the best way to make discoveries that lead to real therapeutics.

Re: A $650M Donation for Psychiatric Research

#6
post #5
post #2

This is a huge donation for the Broad and probably equals all their previous fundraising. I think a lot will ask if it's too much to one institute or too little to solve the problem, but overall I'm very excited. Biology is changing very fast right now, and it's probably the right time for a big new push. Psychiatric disease and brain research is the next big frontier and private funding like this allows places to ta…

I really appreciate that the Broad keeps a lot of attention on basic (or at least, pre-clinical) research. That kind of work is critical to making big discoveries but it's harder to defend for funding in a world where we want to put drugs on shelves. I still want to see drugs on shelves, but starting at the clinic isn't the best way to make discoveries that lead to real therapeutics.

I don't think for psychiatric research we should start with the presumption the end goal is necessarily "drugs on the shelf".

it might or might not be a good goal for some conditions.

Re: A $650M Donation for Psychiatric Research

#8
I was initially worried when the headline said "psychiatric" research, but was pleasantly surprised when I read the article and found out that what they really meant was neuro-biology and its genetic origins, not study of patient behavior. The "top-down" approach has failed psychiatry (or more accurately, psychology) for half a century. I'm glad to see the bottom-up approach (i.e. starting with genes and cells and then working your way up to thoughts/feelings/behaviors) taking the lead.

Re: A $650M Donation for Psychiatric Research

#9
It is a wonderful donation, but I do wish that philanthropists would spend money on lobbying congress and The President to increase science budgets by the billions of dollars per year. Money could also be donated to those running in congress who are favorable to increasing the science budget of NIH, NSF.

Re: A $650M Donation for Psychiatric Research

#10
post #5

Earlier quoted context omitted.

I really appreciate that the Broad keeps a lot of attention on basic (or at least, pre-clinical) research. That kind of work is critical to making big discoveries but it's harder to defend for funding in a world where we want to put drugs on shelves. I still want to see drugs on shelves, but starting at the clinic isn't the best way to make discoveries that lead to real therapeutics.

I don't think for psychiatric research we should start with the presumption the end goal is necessarily "drugs on the shelf". it might or might not be a good goal for some conditions.

That's fair. I was responding to the critique of the Broad is being not very clinical, and that was a figure of speech.
Post reply on HN