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Weightlifting beats running for blood sugar control, researchers find (2025)

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Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#2
(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#3
post #2

(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

Controlled experiments in humans are expensive, time consuming, and actually very difficult to do. Meanwhile any grad student can do a mouse model. The motivation of most academic labs is citations and grants, not useful information. Putting it together…

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#4
post #2

(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

Imagining adorable mice dumbbells

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#5
post #2

(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

Maybe the real value is in training mice to do useful work.

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#6
As this is a mice study it’s worth pointing out humans are particularly adapted for endurance exercise compared to other animals. Not gonna pretend to be a HN expert, but it seems relevant when comparing this sort of thing across species.

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#7
post #2

(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

Imagining adorable mice dumbbells

With enough gains, Pinky & the Brain can finally take over world.

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#8
Dr. Bernstein has long argued this and documents it extensively in his book "Dr. Bernstein's Diabetes Solution"[1]. The main reason being that muscles act like natural glucose sinks that drain sugar directly out of the bloodstream, bypassing the liver, so more muscles = more glucose control.

I highly recommend the introductory chapter to "Dr. Bernstein's Diabetes Solution" by the way, even for non-diabetics. It's basically just the "Life and career" section of his wiki page, but in way more detail -- a really interesting biographical account about an industrial engineer doing diabetes self-experiments with a glucose meter he procured through his wife and going up against the medical community/orthodoxy and failing, only to finally break through when he got a medical degree late in life. I could probably upload and link to just that section if people are interested.

[1] https://en.wikipedia.org/wiki/Richard_K._Bernstein

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#9
post #2

(in mice) - I get it if it’s some new experimental drug, a mouse probably makes sense to test first. With exercise you’d think they could go straight to humans? Seems like it would be more effort getting mice to lift weights than it’s worth.

We still are in the experimental phase about how we can get two groups of human study participants to keep behaving mostly the same, while also complying with the change in exercise we want data on.

Re: Weightlifting beats running for blood sugar control, researchers find (2025)

#10
Luckily, we live in the reality where every human who is interested in how their own body, and not the one of some random mouse, deals with blood sugar, can order a relatively inexpensive (for the benefits it provides) device — a continuous glucose monitor — and gather all the data they need to see what helps controlling the sugar level, and what does not. Using a CGM was a truly life changing experience for me, and I recommend trying it for everyone interested.
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