Live data from Hacker News

The curious case of low-protein diets

knowablemagazine.org

1–10 of 24 posts

Re: The curious case of low-protein diets

#3
> all these data come from nonhuman lab animals

Though what I have see so far is far from everything that could be learned from these surprisingly-humanlike mammals. Still need more research on timing. Maybe protein metabolism is not that different from the better studied methods of derailing glucose metabolism. Maybe the damage is set and done after any prolonged phase of inappropriate diet, and later minor adjustments in consumption have very little additional effect, after controlling for weight and caloric intake.

Maybe all humans need to do is watch their protein intake until puberty.. and then only 60 years later, as failing to retain muscle strength becomes more likely to kill them than any detrimental effect of excessive protein intake.

Re: The curious case of low-protein diets

#4
>Think of the body like a car, suggests Clemence Blouet, a neuroendocrinologist at the University of Cambridge in the UK. You can drive fast, using lots of fuel and putting wear and tear on the auto. Or you can stick to a gentle 15 miles per hour, and the car lasts longer. Living in a high-protein or high-calorie fast lane, she muses, could lead to the accumulation of those pro-aging oxygen radicals. Protein, in particular, also turns on systems that promote growth as well as aging. Restricting the diet could mean fewer of those damaging radicals and less pro-aging actions, keeping the body in smoothly working order for longer.

The implications here for quality of life are pessimistic. Also, the "extension" in the study is about 10%, but driving responsibly can make your car last many times longer.

Re: The curious case of low-protein diets

#5
> Protein dominates the grocery shelves: Protein chips. Protein cookies. Protein water.

Yeah and most of it is incomplete plant protein missing amino acids.

> Protein restriction, Phillips says, is a sort of “lite” version of a more well-known longevity hack — caloric restriction.

I'm confused by this since protein is much lower calorie than fat or carbs.

Re: The curious case of low-protein diets

#6

> Protein dominates the grocery shelves: Protein chips. Protein cookies. Protein water. Yeah and most of it is incomplete plant protein missing amino acids. > Protein restriction, Phillips says, is a sort of “lite” version of a more well-known longevity hack — caloric restriction. I'm confused by this since protein is much lower calorie than fat or carbs.

protein and carbohydrate are both 4 calories per gram?

Re: The curious case of low-protein diets

#7
post #6

> Protein dominates the grocery shelves: Protein chips. Protein cookies. Protein water. Yeah and most of it is incomplete plant protein missing amino acids. > Protein restriction, Phillips says, is a sort of “lite” version of a more well-known longevity hack — caloric restriction. I'm confused by this since protein is much lower calorie than fat or carbs.

protein and carbohydrate are both 4 calories per gram?

Protein serving size is generally lower than carbs in a typical meal. It's not that simple.

Re: The curious case of low-protein diets

#8

> Protein dominates the grocery shelves: Protein chips. Protein cookies. Protein water. Yeah and most of it is incomplete plant protein missing amino acids. > Protein restriction, Phillips says, is a sort of “lite” version of a more well-known longevity hack — caloric restriction. I'm confused by this since protein is much lower calorie than fat or carbs.

>Yeah and most of it is incomplete plant protein missing amino acids.

Common misconception. Soybean, quinoa, buckwheat provide all essential amino acids in good proportions

almost all plant proteins contain all nine essential amino acids, just in lower proportions.

Re: The curious case of low-protein diets

#9
post #4

>Think of the body like a car, suggests Clemence Blouet, a neuroendocrinologist at the University of Cambridge in the UK. You can drive fast, using lots of fuel and putting wear and tear on the auto. Or you can stick to a gentle 15 miles per hour, and the car lasts longer. Living in a high-protein or high-calorie fast lane, she muses, could lead to the accumulation of those pro-aging oxygen radicals. Protein, in part…

Radicals, i think mostly caused by high carbohydrates, ie Advanced Glycation End Products (AGEs) which probably mainly are generated by overconsumotion of carbohydrates.

You can have a keto/carnivore diet which, will minimize AGEs, is the meat/protein actually bad for you? (Assuming you avoid the std diet carb overconsumption ofc)

Post reply on HN