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Human brain changes after first psilocybin use

nature.com

1–10 of 16 posts

Re: Human brain changes after first psilocybin use

#4

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

> Microdosing can literally be a lifesaver

> All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo.

Re: Human brain changes after first psilocybin use

#5

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

Have they figured out a way around the interactions with SSRIs yet?

Re: Human brain changes after first psilocybin use

#6

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

Re: Human brain changes after first psilocybin use

#7

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

5 grams is considered a heroic dose (e.g. the dose where you are likely to experience things like ego death).

Around 2 grams is considered a "museum dose" or "social dose" (e.g. it's enough to change your perceptions but not so much that you are unable to operate).

So 25 mg is a fairly low dose while 1 mg is very low.

Re: Human brain changes after first psilocybin use

#8

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

they sell psilocybin gummies, ranging from weak to 4.5g per. The ones i've tried were "3 is a normal dose, 6 is space jam, 1 is a nice afternoon off." I took one, and it did make everything a little brighter, birds sweeter sounding, and everything seemed a little bit better for a while. But i don't trust the manufacturers, so i only tried 1 pack over a couple of weeks.

anyhow 1-25mg is a pretty small does if 5g is considered a hero dose per siblings.

I haven't tried tons of nootropics like this, but i have tried Kanna, Kratom, psilocybin, CBD, delta-9 THC, THC-P, hydrogenated THC, salvia, and i'm probably forgetting a lot. Belladonna, that's one i tried before, for example. just came to me.

I don't do "hard" drugs, though, never have, no desire to. I do like plants, though.

Re: Human brain changes after first psilocybin use

#9

Earlier quoted context omitted.

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

5 grams is considered a heroic dose (e.g. the dose where you are likely to experience things like ego death). Around 2 grams is considered a "museum dose" or "social dose" (e.g. it's enough to change your perceptions but not so much that you are unable to operate). So 25 mg is a fairly low dose while 1 mg is very low.

5 grams of mushrooms is not the same as 5 grams of psilocybin. When taking about mg, I think they mean psilocybin. When talking about grams, it's mushrooms

Re: Human brain changes after first psilocybin use

#10

Earlier quoted context omitted.

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

5 grams is considered a heroic dose (e.g. the dose where you are likely to experience things like ego death). Around 2 grams is considered a "museum dose" or "social dose" (e.g. it's enough to change your perceptions but not so much that you are unable to operate). So 25 mg is a fairly low dose while 1 mg is very low.

I looked at the study and it appears that it's 25 mg of synthetic psilocybin. So assuming that's equivalent to 100% psilocybin and mushrooms average around .6% dry then it would be like 4g dry mushrooms.
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