Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
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Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#2Great to see an example of concrete evidence that physicians made changes when the evidence showed a change was needed.
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#3Low-dode aspirin wrecks the stomach or small intestine anyway in many individuals, irrespective of its form. This strikes a lot sooner than internal bleeding. Both the chewable and the enteric-coated forms cause this injury at separate locations.
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#4Low-dode aspirin wrecks the stomach or small intestine anyway in many individuals, irrespective of its form. This strikes a lot sooner than internal bleeding. Both the chewable and the enteric-coated forms cause this injury at separate locations.
It doesn't, as it doesn't dissolve in the stomach, thanks to its enteric coating.
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#5Great to see an example of concrete evidence that physicians made changes when the evidence showed a change was needed.
This "evidence" is highly questionable. There's other evidence, i.e., that taking aspirin with DGL or vitamin C does not damage the stomach lining, have led to new formulations decades ago. In fact, high doses of aspirin have been sold in Europe combined with vitamin C for as long as I remember - Aspirin C by Bayer and Upsarin C by UPSA. There's other evidence, too, that aspirin protects against cancer.
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#6Great to see an example of concrete evidence that physicians made changes when the evidence showed a change was needed.
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Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#7Low-dode aspirin wrecks the stomach or small intestine anyway in many individuals, irrespective of its form. This strikes a lot sooner than internal bleeding. Both the chewable and the enteric-coated forms cause this injury at separate locations.
>in many individuals,
So then why are we not working to determine which individuals it is suitable for?
What is the alternative to aspirin for this use case and who benefits?
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#8Low-dode aspirin wrecks the stomach or small intestine anyway in many individuals, irrespective of its form. This strikes a lot sooner than internal bleeding. Both the chewable and the enteric-coated forms cause this injury at separate locations.
>in many individuals, So then why are we not working to determine which individuals it is suitable for? What is the alternative to aspirin for this use case and who benefits?
One just finds out by trial and error, although the injury can take many months to manifest, and is slowly reversible upon cessation. As for the safer pharmaceutical alternative, clopidogrel is it, again in a sufficiently low dose, but it is not OTC.
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#9guessing ozympic, statins, and stomach staples + pretty reliable stats about causing internal bleeding
Re: Low-Dose Aspirin Usage for Primary Prevention Has Fallen by >50% Since 2018
#10Great to see an example of concrete evidence that physicians made changes when the evidence showed a change was needed.
This "evidence" is highly questionable. There's other evidence, i.e., that taking aspirin with DGL or vitamin C does not damage the stomach lining, have led to new formulations decades ago. In fact, high doses of aspirin have been sold in Europe combined with vitamin C for as long as I remember - Aspirin C by Bayer and Upsarin C by UPSA. There's other evidence, too, that aspirin protects against cancer.
My understanding is the bleeding risk associated with aspirin can be addressed by taking Vitamin K.