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The optimal age to freeze eggs is 19

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Re: The optimal age to freeze eggs is 19

#2
> Lastly, the stem cells we're planning to use to make these eggs accrue mutations with age, and we don't currently have a good method to fix these before making them into eggs. These mutations will bring additional risk of various serious diseases, only some of which we currently have the genetic screening to detect.

I've always found this one fascinating. Somehow human cells age and humans get old and die but humans can somehow make an entirely new creature through reproduction where that is reset and most of the defects from the parent are gone as well.

How does that work and what stumbling blocks exist that prevent us from replicating it?

Re: The optimal age to freeze eggs is 19

#4
post #2

> Lastly, the stem cells we're planning to use to make these eggs accrue mutations with age, and we don't currently have a good method to fix these before making them into eggs. These mutations will bring additional risk of various serious diseases, only some of which we currently have the genetic screening to detect. I've always found this one fascinating. Somehow human cells age and humans get old and die but human…

Isn’t that what stem cell therapy is?

Re: The optimal age to freeze eggs is 19

#5
post #2

> Lastly, the stem cells we're planning to use to make these eggs accrue mutations with age, and we don't currently have a good method to fix these before making them into eggs. These mutations will bring additional risk of various serious diseases, only some of which we currently have the genetic screening to detect. I've always found this one fascinating. Somehow human cells age and humans get old and die but human…

I don't know anything about this subject, but I thought it was just natural selection that effectively filtered out the 'bad eggs', as it were. On that same note, I've worried about the effects that modern medicine might have in short-circuiting evolution/natural selection. Would love to hear from someone with qualifications to speak on this matter.

Re: The optimal age to freeze eggs is 19

#7
post #2

> Lastly, the stem cells we're planning to use to make these eggs accrue mutations with age, and we don't currently have a good method to fix these before making them into eggs. These mutations will bring additional risk of various serious diseases, only some of which we currently have the genetic screening to detect. I've always found this one fascinating. Somehow human cells age and humans get old and die but human…

We’re were photocopying photocopies. But I guess if you’re taking two copies and tracing a third that is based on them but doesn’t actually have to be a facsimile, it gives nature more flexibility?

Like I’m not sure it actually works this way but I can intuit why it’s possible, given the new life doesn’t have to be an exact replication.

Re: The optimal age to freeze eggs is 19

#8
post #2

> Lastly, the stem cells we're planning to use to make these eggs accrue mutations with age, and we don't currently have a good method to fix these before making them into eggs. These mutations will bring additional risk of various serious diseases, only some of which we currently have the genetic screening to detect. I've always found this one fascinating. Somehow human cells age and humans get old and die but human…

Naturally the reset happens before most cells have grown, part of the trick in doing it with grown humans is doing so without destroying existing tissue or causing cancer.

It's almost like trying to change the flavor of a cake after it's been baked. Significantly easier to swap out ingredients before it's that far in the process.

Re: The optimal age to freeze eggs is 19

#10

It's wild that in the year 2026 modern science can't recreate a SINGLE cell (which is what a human egg/ovum is).

it's possible to convert stem cells or skin cells into functional egg cells (ova) in lab settings, though the technology remains experimental and not yet ready for routine clinical use
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