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Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

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Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#4

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I'm not a woman, but I wonder how necessary pap smears (one of the most invasive procedures to which women are routinely subjected) are if everyone's vaccinated against HPV? https://www.cuimc.columbia.edu/news/cervical-cancer-screenin...

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#6

[flagged]

There are people who will do the right thing, there will be people who you can teach to do the right thing, and there will be people who will ignore you no matter what. Optimize for the first two. "Pick better parents" is unfortunately unactionable advice.

Australia has almost eradicated cervical cancer through HPV vaccination efforts, other countries will get there as a function of uptake and cohort replacement. There is a recently developed blood test that can detect the biomarkers from HPV related cancers years before they would traditionally be diagnosed, but prevention via vaccination remains key.

https://www.who.int/news/item/17-11-2023-global-partners-che...

https://www.thelancet.com/journals/lanpub/article/PIIS2468-2...

https://en.wikipedia.org/wiki/HPV_vaccine

https://academic.oup.com/jnci/advance-article-abstract/doi/1... | https://doi.org/10.1093/jnci/djaf249

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#8

The goal wasn't to eliminate the HPV strains, it was to decrease cervical cancer. Has Denmark encountered a drop in cervical cancer? If so, that's a great outcome!

This seems to have some data that suggests they have seen a decline: https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.35081

There's a chart about 2/3 down the page that shows a drop in several age groups, and a particularly striking drop in the 20-29 age group: https://onlinelibrary.wiley.com/cms/asset/fd3e820c-4610-4c4e...

Re: Denmark close to wiping out cancer-causing HPV strains after vaccine roll-out

#10

Good news. Bad news is that many countries came close to wiping out measles et al. too, but it takes sustained effort to keep things like that.

Unlike the measles, HPV is not a good eradication candidate due to the existence of non-human reservoirs.
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