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'Gwada negative': French scientists find new blood type in woman

lemonde.fr

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Re: 'Gwada negative': French scientists find new blood type in woman

#2

Post by ajb »

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es...

Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

Re: 'Gwada negative': French scientists find new blood type in woman

#3

Post by xattt »

ajb wrote: post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

Neither article talks about whether this is a minor or a major antigen.

Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening.

Minor antigens come into play when crossmatching for infants and premies, but this is way beyond my scope.

Re: 'Gwada negative': French scientists find new blood type in woman

#4

Post by yorwba »

xattt wrote: post #3
ajb wrote: post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and pr…

With a single known case of somebody producing antibodies against the antigen, it might be a bit hard to say how many transfusions it typically takes to develop a sensitivity.

Re: 'Gwada negative': French scientists find new blood type in woman

#6

Post by JackFr »

xattt wrote: post #3
ajb wrote: post #2

The OP is low on details. There is more in this article (in french): https://www.lindependant.fr/2025/06/21/il-ny-a-quelle-qui-es... Apparently the ISBT have added this to their list: https://www.isbtweb.org/isbt-working-parties/rcibgt.html (the page still says 47 but the data tables have it added)

Neither article talks about whether this is a minor or a major antigen. Blood for transfusion needs to be crossmatched against antigen types of the recipient. Many patients will tolerate several transfusions of a minor mismatched antigen before developing a sensitivity. Major antigens are what cause significant reactions that can be life-threatening. Minor antigens come into play when crossmatching for infants and pr…

I recently had major surgery and got two units of blood in during the operation and two more post-op. Post-op before I got the blood, they typed my blood again, and a nurse stayed in the room while I got the blood and I wondered why. This comment makes it clear.
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