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Using a BCI with LLM for enabling ALS patients to speak again with family

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Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#5
Are there any details on how this works? Based on what is available in the linked article, it looks like they have an LLM+RAG and are trying to pass off the responses as speech from the user. Done with full transparency, and right protections, this could be useful, but calling it BCI, and overselling it as user's voice (especially given voice cloning is also being done) can be misrepresenting it.

Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#6
post #5

Are there any details on how this works? Based on what is available in the linked article, it looks like they have an LLM+RAG and are trying to pass off the responses as speech from the user. Done with full transparency, and right protections, this could be useful, but calling it BCI, and overselling it as user's voice (especially given voice cloning is also being done) can be misrepresenting it.

seems like they have built on top of HALO using generative AI now (with partnership from unababel?)

Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#7
post #5

Are there any details on how this works? Based on what is available in the linked article, it looks like they have an LLM+RAG and are trying to pass off the responses as speech from the user. Done with full transparency, and right protections, this could be useful, but calling it BCI, and overselling it as user's voice (especially given voice cloning is also being done) can be misrepresenting it.

Agreed - I don't want to come across as negative, but this is certainly in the "extraordinary claims" category for me right now. If this works, it's obviously huge, but I really want to see third party validation before I can let go of my skepticism.

I would be very curious to hear about interviews with the patients (conducted through their current means of communication, eg: eye gaze interfaces). Are they finding that the speech generated by the system reflects their intentions accurately?

EDIT: the EEG peripheral they are using is 4 channels / 250 Hz sample rate. I freely admit I have little knowledge of neuroscience and happily defer to the experts, but that really doesn't seem like a lot of data to be able to infer speech intentions.

Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#8
Those non-invasive headbands (which work very differently from implanted electrodes) are notoriously inaccurate at recording brain signals. Even scientific studies, which use advanced setups like the 10-20 system for scalp EEG, face unsolved challenges in removing noise from the data and in using the data to reconstruct underlying brain activity [0] – let alone making meaningful inferences about it.

Patients with locked-in syndrome (one of the use cases mentioned in the article, also called a pseudo-coma), or with other disorders of consciousness, are unable to protest, or to confirm the accuracy of the generative message which is being attributed to them. Communicating on your own terms and in your own words is fundamental to human dignity.

Meanwhile, this coincides with lukewarm reception of generative AI from consumers; perhaps it is the lack of autonomy of locked-in patients, which makes them an interesting segment to this new generation of ventures, scrambling for a ROI on the enormous over-investment in the sector.

The conference venues look lush tho.

[0] https://en.wikipedia.org/wiki/Electroencephalography#Artifac...

Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#9
post #8

Those non-invasive headbands (which work very differently from implanted electrodes) are notoriously inaccurate at recording brain signals. Even scientific studies, which use advanced setups like the 10-20 system for scalp EEG, face unsolved challenges in removing noise from the data and in using the data to reconstruct underlying brain activity [0] – let alone making meaningful inferences about it. Patients with loc…

I've spoken to a lot of smart people on the topic of EEG (I'm in a very related field). I agree with you.

It's an extremely powerful tool for diagnosis of a limited range of conditions but it is not magic. Electrical signal gets attenuated heavily when signals are not on the outside of the brain. Even still, a headband like this is susceptible to noise from movement and other factors. You either need to correct for this with AI, which introduces a second source for error, or you need a very still user. I'm not convinced by the ability to "read minds" with the technology; I would need the man in the video answer some specific questions to be convinced.

Is this better than not being able to communicate at all? Yes.

Re: Using a BCI with LLM for enabling ALS patients to speak again with family

#10
post #7
post #5

Are there any details on how this works? Based on what is available in the linked article, it looks like they have an LLM+RAG and are trying to pass off the responses as speech from the user. Done with full transparency, and right protections, this could be useful, but calling it BCI, and overselling it as user's voice (especially given voice cloning is also being done) can be misrepresenting it.

Agreed - I don't want to come across as negative, but this is certainly in the "extraordinary claims" category for me right now. If this works, it's obviously huge , but I really want to see third party validation before I can let go of my skepticism. I would be very curious to hear about interviews with the patients (conducted through their current means of communication, eg: eye gaze interfaces). Are they finding t…

Even if the LLM hallucinates every word, just knowing when to say something versus stay quiet based on EEG data would be a huge breakthrough.
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