Ask HN: Niches Underserved by Programmers?

I'm thinking about starting a company that does programming work for areas of society that normally don't have the best software to work with. I've read stories of code in science labs running orders of magnitude longer than it should because of bad algorithms, for example. What other niches are there like this, which could be served by a business that seeks them out? Currently I'm thinking of science and medicine, though the latter has the additional hurdle of certification and other bureaucratic obstacles.

Underserved how? What software do they use that could be improved?