Live data from Hacker News

"Outrageously" priced weight-loss drugs could bankrupt US health care

arstechnica.com

1–10 of 102 posts

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#2
> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month.

Serious question: Why not just bootleg the stuff?

It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and you'll find a million places that sell it at $25 for a month's supply. Those vendors are legitimate far more often than not.

If Novo Nordisk won't sell to humans at a humane price -- instead preferring to gouge insurance companies and the gatekeeping medical bureaucracy -- I'd argue that there's a moral imperative to bootleg the drug and distribute it to those who would benefit from it at a fair price.

And, unlike many of the bodybuilding drugs (which are a big business,) these new weight-loss drugs aren't scheduled, so you won't get in much trouble even in the unlikely event you are caught.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#3

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

Patents?

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#4

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

These same companies that manufacture and distribute BPC-157 and bodybuilding drugs already also offer various GLP1 drugs, semaglutide, tirzepatide, retatrutide. Google around and you can find them available for much cheaper via grey market vendors.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#5

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

They already are. Weight loss clinics will send the Rx to a compounding pharmacy.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#7
post #4

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

These same companies that manufacture and distribute BPC-157 and bodybuilding drugs already also offer various GLP1 drugs, semaglutide, tirzepatide, retatrutide. Google around and you can find them available for much cheaper via grey market vendors.

Well, there you go, I guess.

So high semaglutide pricing won't end up "bankrupting" the US medical system. It'll push an ever larger number of patients -- and more than a few well-meaning doctors, who already recommend things like BPC-157 -- into the gray market. That this would further delegitimize the medical establishment and FDA would be a well-deserved outcome.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#8

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

They already are. Weight loss clinics will send the Rx to a compounding pharmacy.

>clinics will send the Rx to a compounding pharmacy.

I think you are confused about what a compounding pharmacy is -- at least if you refer to how it works in the US.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#9

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

Patents?

I believe the most likely outcome is a price curve downwards as Novo nordisk is quietly forced info JV with US manufacturers under implicit threat of some one-off ruling akin to an IPR eminent domain action.

Nobody in government wants to accept IPR is broken but they'll find a way to bend it's ruling into a hoop, for the specific needs of the moment.

Re: "Outrageously" priced weight-loss drugs could bankrupt US health care

#10

> A study by researchers at Yale estimated that drugs like Wegovy can be profitably manufactured for less than $5 per month. Serious question: Why not just bootleg the stuff? It's a very small protein, easy to make, and "research chemical" companies that sell structurally similar bodybuilding drugs and nootropics are a dime a dozen. Search online for "BPC-157" (a protein drug of only slightly inferior complexity) and…

> I'd argue that there's a moral imperative to bootleg the drug and distribute it to those who would benefit from it at a fair price.

Why not do away with patents and IP altogether if the standard is that as soon as someone makes something needed it can be stolen?

Post reply on HN