Sleep does not help brain wash out toxins, study suggests
theguardian.com
Sleep does not help brain wash out toxins, study suggests
1–10 of 35 posts
Re: Sleep does not help brain wash out toxins, study suggests
#2Obviously the article leave a lot of the science out, but this sounds like it’d be an easy thing to test for (which they’ve now done). Why wouldn’t this have been done years ago - I’m not trying g to say they should have done it earlier, as I genuinely don’t know. Is the tech to check this new? How much other science has been based off of this theory in the meantime?
Re: Sleep does not help brain wash out toxins, study suggests
#3What about this?
Sleep Drives Metabolite Clearance from the Adult Brain (2014)
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880190/
> Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural sleep or anesthesia are associated with a 60% increase in the interstitial space, resulting in a striking increase in convective exchange of cerebrospinal fluid with interstitial fluid. In turn, convective fluxes of interstitial fluid increased the rate of β-amyloid clearance during sleep. Thus, the restorative function of sleep may be a consequence of the enhanced removal of potentially neurotoxic waste products that accumulate in the awake central nervous system.
Re: Sleep does not help brain wash out toxins, study suggests
#4What about this, from a month ago:
https://arstechnica.com/science/2024/04/sleeping-more-flushe...
Which seems to very clearly show that the brain flushes things out when we're asleep.
Re: Sleep does not help brain wash out toxins, study suggests
#5I have anecdotal evidence from a long term study (~40 years) that suggests otherwise hahaha! :) tho I know some amount of sleep can reduced naturally using certain forms of seated meditation.
Re: Sleep does not help brain wash out toxins, study suggests
#6What about this? Sleep Drives Metabolite Clearance from the Adult Brain (2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880190/ > Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural sleep or anesthesia are associated with a 60% increase in the interstitial space, resulting in a striking increase in convective exchange of cerebrospinal fluid with…
Exactly, the flushing effect. Which you can also feel when you do some forms of meditation :)
Re: Sleep does not help brain wash out toxins, study suggests
#7What about this, from a month ago: https://arstechnica.com/science/2024/04/sleeping-more-flushe... Which seems to very clearly show that the brain flushes things out when we're asleep.
It doesn't show that.
All your article says is that neuron trigger the gylmphatic system to create waves.
It doesn't establish that the waves actually remove more waste product.
It doesn't even actually establish that the waves cause more flow. They are simply a "plausible mechanism to explain the correlated flow".
Re: Sleep does not help brain wash out toxins, study suggests
#8What about this? Sleep Drives Metabolite Clearance from the Adult Brain (2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880190/ > Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural sleep or anesthesia are associated with a 60% increase in the interstitial space, resulting in a striking increase in convective exchange of cerebrospinal fluid with…
Exactly, the flushing effect. Which you can also feel when you do some forms of meditation :)
I'm curious - do you have a physical sensation when this happens to you? Is there any evidence to support this claim? I ask because I often feel similar to brushing my teeth when I meditate, it's hard to explain though.
Re: Sleep does not help brain wash out toxins, study suggests
#9What about this? Sleep Drives Metabolite Clearance from the Adult Brain (2014) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3880190/ > Using real-time assessments of tetramethylammonium diffusion and two-photon imaging in live mice, we show that natural sleep or anesthesia are associated with a 60% increase in the interstitial space, resulting in a striking increase in convective exchange of cerebrospinal fluid with…
That paper is referenced in the one linked. The authors are not unaware of it.
Re: Sleep does not help brain wash out toxins, study suggests
#10*toxicants