Why haven't we cured cancer yet?
sciencebasedmedicine.org
Why haven't we cured cancer yet?
1–10 of 167 posts
Re: Why haven't we cured cancer yet?
#2... Because the "smart" people work on Wall Street/for consulting firms.
... Because Facebook acquired Instagram.
Re: Why haven't we cured cancer yet?
#3Re: Why haven't we cured cancer yet?
#4We can't even "cure" a relatively simple virus like the cold or influenza, and cancer is like 10,000x times more complicated - gotta respect all the hackers who're working in the medical field...
Re: Why haven't we cured cancer yet?
#5Some things are meant to take time and be right. First time.
Survival rates are spectacularly better than they were fifteen or twenty years ago and they are getting better all the time.
Also there is no one type of lung cancer, brain tumour or bladder or bowel cancer either. There are many different types. Half the battle is identifying (and successfully treating) the right sort.
I still think there will be cancer in fifty years time. But we won't have to die from it. We may never eradicate it though, because it is a tough, complex bio-engineering problem, closely allied to programmed cell death and immortality. That's another tough nut to crack for the same reasons, inexorably intertwined as they are.
Re: Why haven't we cured cancer yet?
#6TLDR: Breast cancers, for instance, have been shown to harbor at least 1,700 different mutations, but only three of them showed up in at least 10% of patients, with the great majority of them being unique to each patient. The most recent study in Nature discussed above shows that even a single subtype of breast cancer that is generally treated clinically more or less the same, TNBC, varies wildly (and almost continuously) in the genomic changes and mutations each tumor has. Not only that, but each TNBC is in essence several diseases, because each TNBC is made up of many different clones that have evolved as the tumor itself grew, progressed, and evolved. All of this occurs even before the tumor has been subjected to any treatment at all. As if that’s not bad enough, it would appear that tumors are a mosaic of groups of many different tumor cell types that develop through branching evolution such that metastases can be very different from the primary tumor and even different regions of the primary tumor can be very different from each other, so much so that finding a “favorable prognosis signature” on a core biopsy means only that that one area biopsied has that gene signature. Large areas elsewhere in the tumor could have the unfavorable prognosis signature.
And even more interesting if you look at the history of a tumor the mutations goes back for a fairly long time, possibly on the order of 30+ years. While it may not be an actual cure, removing abnormal cells early may be more effective than trying to treat cancer in the last 1-10% of it's lifetime when it's already become a diversified killing machine.
Re: Why haven't we cured cancer yet?
#7The National Cancer Institute's average yearly budget for cancer research is around $4.9 billion. NFL football revenue? $9 billion. Priorities.
Re: Why haven't we cured cancer yet?
#8The National Cancer Institute's average yearly budget for cancer research is around $4.9 billion. NFL football revenue? $9 billion. Priorities.
Re: Why haven't we cured cancer yet?
#9But seriously It's the money that keeps us from curing cancer, or lack thereof. Nothing else. As human beings we really need to decide what's more important....Wealth or our survival and wellbeing. We're too smart as a society to let things like lack of money keep us from curing disease and exploring other planets.
Re: Why haven't we cured cancer yet?
#10The National Cancer Institute's average yearly budget for cancer research is around $4.9 billion. NFL football revenue? $9 billion. Priorities.