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A miracle drug sold over the counter

trevorklee.substack.com

1–10 of 21 posts

Re: A miracle drug sold over the counter

#2
The LD50 of caffeine for my cat is approximately ten Monster Energy drinks?To an untrained mind, that simultaneously seems like a lot and not much at all. I guess given my cat is 1/10th my weight, that’s like me having 100, which feels like it should kill me.

Holy crap. A Dunkin Donuts Large Ice Coffee is 396mg of caffeine. That’s insane. That’s 4.5 Red Bulls.

I originally felt a wee bit dismissive of the article’s thesis. But wow, we are absolutely cranking up the caffeine content. I remember Jolt or Bawls or other drinks in high school being edgy because they had “twice the caffeine” (about 80mg for 355ml can).

But now we’ve got 400mg in a single beverage.

Is this a feedback loop? We keep increasing caffeine content because we need more for our beverages to have the desired effect for customers?

Re: A miracle drug sold over the counter

#6
post #4

A tiny amount of caffeine (in 1 can of a soft drink like Coke) can wreck my sleep for 24 hours. And I love caffeine. Sigh.

I’ve struggled with sleep for so long that I’m basically one big, tired Petri dish.

I’ve found the same in my experiments, which surprised me: 100mg of caffeine between 7-11am is enough to make sleep impossible until maybe 3-4am. Meanwhile my wife can have 200mg at 7pm and be out by 10. I knew caffeine did this but I thought such a small amount so early in the day would easily be gone by night.

Next I want to somehow measure caffeine content over time and get a feel for how fast my body processes it. I also want to experiment with media (hot drinks, cold drinks, pills, etc.) I love caffeine.

Re: A miracle drug sold over the counter

#7
post #5

I liked the build up, but > The drug that I’m thinking of is currently predominantly used as a pesticide Is that true? I would think it's predominantly used as a drink additive...

> Is that true?

Plants use caffeine to kill bugs.

CGP Grey video on the matter: https://www.youtube.com/watch?v=OTVE5iPMKLg&t=69s

Re: A miracle drug sold over the counter

#8
post #5

I liked the build up, but > The drug that I’m thinking of is currently predominantly used as a pesticide Is that true? I would think it's predominantly used as a drink additive...

It might be true if you (like the author, at least that's my interpretation) include the use by the original plants, which I guess occurs until the plant is (destructively, which I'm not sure how common it is) harvested.

Re: A miracle drug sold over the counter

#9
post #4

A tiny amount of caffeine (in 1 can of a soft drink like Coke) can wreck my sleep for 24 hours. And I love caffeine. Sigh.

Try taking l-theanine in conjunction. About half as much theanine as caffeine. See: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480845/
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