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Pfizer and Moderna vaccines may produce lasting immunity

nature.com

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Re: Pfizer and Moderna vaccines may produce lasting immunity

#4
This is great news, adding to a report in Nature that the natural immunity produced in people who have already had covid may last a lifetime.[1]

In case you hadn't heard, the Cleveland Clinic--consistently regarded as one of the top hospital systems in the United States and in the world--recently shared a study of 52,238 patients showing zero incremental benefit from the jab to the previously infected, recommending that "people who’ve had COVID-19 don’t need to get vaccinated."[2]

[1]https://www.nature.com/articles/d41586-021-01442-9

[2]https://www.healthline.com/health-news/new-study-determines-...

Re: Pfizer and Moderna vaccines may produce lasting immunity

#5
The mRNA vaccines have been the silver lining to the whole COVID-19 disaster.

They seem “unreasonably effective” against COVID, basically if you had a genie that you could ask to make a vaccine, it would be hard to do much better, other than the requirement for 2 jabs.

In addition, the mRNA technology has broad applicability to other issues such as other viruses (such as flu) and even cancer!

Re: Pfizer and Moderna vaccines may produce lasting immunity

#6

We’ll still probably need periodic booster shots to deal with variants as they crop up. Still, very encouraging news if it holds up in practice.

We'll "need" to take periodic boosters to improve Moderna and Pfizer's profit margins.

That said, given its safe, I'm happy to do it to help fund / drive investment into the mRNA supply chain.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#7

The mRNA vaccines have been the silver lining to the whole COVID-19 disaster. They seem “unreasonably effective” against COVID, basically if you had a genie that you could ask to make a vaccine, it would be hard to do much better, other than the requirement for 2 jabs. In addition, the mRNA technology has broad applicability to other issues such as other viruses (such as flu) and even cancer!

Do we have any proof that the second dose is useful at all ?

Re: Pfizer and Moderna vaccines may produce lasting immunity

#8
post #4

This is great news, adding to a report in Nature that the natural immunity produced in people who have already had covid may last a lifetime.[1] In case you hadn't heard, the Cleveland Clinic--consistently regarded as one of the top hospital systems in the United States and in the world--recently shared a study of 52,238 patients showing zero incremental benefit from the jab to the previously infected, recommending t…

It's time for the naturally immune to be treated the same as those who've been vaccinated. There is absolutely zero scientific evidence to the contrary, and plenty of evidence to support it.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#9
post #7

The mRNA vaccines have been the silver lining to the whole COVID-19 disaster. They seem “unreasonably effective” against COVID, basically if you had a genie that you could ask to make a vaccine, it would be hard to do much better, other than the requirement for 2 jabs. In addition, the mRNA technology has broad applicability to other issues such as other viruses (such as flu) and even cancer!

Do we have any proof that the second dose is useful at all ?

Yes, this was covered in the trials for both vaccines.

Re: Pfizer and Moderna vaccines may produce lasting immunity

#10

We’ll still probably need periodic booster shots to deal with variants as they crop up. Still, very encouraging news if it holds up in practice.

We'll "need" to take periodic boosters to improve Moderna and Pfizer's profit margins. That said, given its safe, I'm happy to do it to help fund / drive investment into the mRNA supply chain.

I would caution you to reconsider "given it's safe" as a statement. I think the proper statement might be closer to "the benefits can outweigh the risks, depending on the disease being treated". There are growing bodies of evidence that spike proteins travel throughout your body, don't stay isolated at the injection site, and can cause severe reactions in some people (see incidents of heart inflammation, etc). I was skeptical myself until I got the first shot and am currently on day 5 of chest pain and shortness of breath. I have a family friend (30's, semi-professional athlete) who just had a massive heart attack 5 days after vaccination, with an otherwise healthy cardio system. Lots of anecdata, can't make good policy with it, but we are still flying by the seat of our pants and don't know the overall landscape.

For what it's worth I'm optimistic, especially around customized cancer treatments, I am just cautiously pessimistic about the overall safety of causing your body to build a ton of spike proteins and have them float around. In other words, for "minor" illnesses like flu, it might not be a net benefit.

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