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Pfizer vaccine reprograms innate immune responses

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Re: Pfizer vaccine reprograms innate immune responses

#4
post #3

I'm honestly pretty torn at this point which vaccine I should be going for. It seems like every week there is another article insinuating that there is some poorly understood, potentially high impact, facet of a given vaccine. Anyone else "holding out?"

Not being an expert in the subject, but a lot of the COVID vaccines are based on established and well-tested mechanisms that AFAIK, are fairly predictable.

Re: Pfizer vaccine reprograms innate immune responses

#5
post #3

I'm honestly pretty torn at this point which vaccine I should be going for. It seems like every week there is another article insinuating that there is some poorly understood, potentially high impact, facet of a given vaccine. Anyone else "holding out?"

I'm also holding out

Re: Pfizer vaccine reprograms innate immune responses

#7
post #3

I'm honestly pretty torn at this point which vaccine I should be going for. It seems like every week there is another article insinuating that there is some poorly understood, potentially high impact, facet of a given vaccine. Anyone else "holding out?"

I'm waiting.

Re: Pfizer vaccine reprograms innate immune responses

#9
post #8

Is "reprograms innate immune responses" not just another way of saying it does what a vaccine is supposed to? All I got from it was that it might cause you to react more strongly to fungal infections.

“Innate immunity” is a particular thing in immunology that’s distinct from “adaptive immunity”. Adaptive immunity includes things like antibodies, and is most often what we are targeting with vaccines. Innate immunity covers a huge range of inherited systems including hard-codes responses to things like bacterial proteins, markers for fungi and viruses, etc

Like everything else in biology, there is tight coupling between innate immunity and adaptive immunity), so the distinction in reality isn’t so clear-cut about what’s part of innate vs adaptive, but that’s the broad gist.

Re: Pfizer vaccine reprograms innate immune responses

#10
post #3

I'm honestly pretty torn at this point which vaccine I should be going for. It seems like every week there is another article insinuating that there is some poorly understood, potentially high impact, facet of a given vaccine. Anyone else "holding out?"

Unless you are a researcher in the field, there are certainly more important things for you to be worrying about. Just get a vaccine, any vaccine.
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