The most effective malaria vaccine yet discovered

#1

Post by hprotagonist » Fri, Apr 23, 2021, 4:13 PM UTC

The most effective malaria vaccine yet discovered
blogs.sciencemag.org

Re: The most effective malaria vaccine yet discovered

#2

Post by chmod600 » Fri, Apr 23, 2021, 4:33 PM UTC

Are any of the mosquito extinction approaches being seriously tried? Genetic engineering, etc.?

Re: The most effective malaria vaccine yet discovered

#3

Post by Darmody » Fri, Apr 23, 2021, 4:44 PM UTC

chmod600 wrote: post #2

Are any of the mosquito extinction approaches being seriously tried? Genetic engineering, etc.?

https://www.bbc.com/news/world-us-canada-53856776

Re: The most effective malaria vaccine yet discovered

#4

Post by FredPret » Fri, Apr 23, 2021, 4:46 PM UTC

chmod600 wrote: post #2

Are any of the mosquito extinction approaches being seriously tried? Genetic engineering, etc.?

I, for one, have been going at them one at a time for years now

Re: The most effective malaria vaccine yet discovered

#5

Post by eloff » Fri, Apr 23, 2021, 5:03 PM UTC

What blows me away is in a study group of 734 infants, which benefited from maternal antibodies against malaria, 717 were infected by malaria in the first year of their life. That's nearly 100%, in the first year since birth. That's devastating.

The vaccine is showing 77% efficacy in trials in Burkina Faso.

That's an ongoing pandemic that makes covid-19 look like a case of the sniffles. Malaria deaths peaked around 930,000 a year in 2004, and is around 600,000 a year now. I believe covid-19 death toll stands around 3 million deaths, most above the age of 70. Malaria is over 100 million, most under the age of 5.

Source: https://ourworldindata.org/malaria

Re: The most effective malaria vaccine yet discovered

#6

Post by _Microft » Fri, Apr 23, 2021, 5:05 PM UTC

For comparison, the mentioned "RTS,S" vaccine has an efficacy "from 26 to 50% in infants and young children", see https://en.wikipedia.org/wiki/RTS,S

Re: The most effective malaria vaccine yet discovered

#7

Post by ska » Fri, Apr 23, 2021, 5:15 PM UTC

chmod600 wrote: post #2

Are any of the mosquito extinction approaches being seriously tried? Genetic engineering, etc.?

Seriously tried, yes. Seriously effective, no (at least so far). At least that was the state of things last I looked a few years ago.

Re: The most effective malaria vaccine yet discovered

#8

Post by bolangi » Fri, Apr 23, 2021, 5:18 PM UTC

chmod600 wrote: post #2

Are any of the mosquito extinction approaches being seriously tried? Genetic engineering, etc.?

Widespread supply of mosquito nets treated with an insecticide is one of the more successful measures.

Re: The most effective malaria vaccine yet discovered

#9

Post by grecy » Fri, Apr 23, 2021, 5:27 PM UTC

Having personally had Malaria twice, I am elated at this news.

It was fascinating to experience it from "the inside" in Africa, and attempt to understand how essentially everyone gets it, every single year. It's simply a part of life there.

Re: The most effective malaria vaccine yet discovered

#10

Post by vanderZwan » Fri, Apr 23, 2021, 5:31 PM UTC

eloff wrote: post #5

What blows me away is in a study group of 734 infants, which benefited from maternal antibodies against malaria, 717 were infected by malaria in the first year of their life. That's nearly 100%, in the first year since birth. That's devastating. The vaccine is showing 77% efficacy in trials in Burkina Faso. That's an ongoing pandemic that makes covid-19 look like a case of the sniffles. Malaria deaths peaked around 9…

Although I am Dutch, I was born in Ghana. My parents worked in a local hospital as doctors. If you can expect anyone to be extremely cautious and in the position to be able to act on it, it would be them. Still got malaria before I turned one.