Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
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Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#2How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#3How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
They measure obesity and find it 0.02 vs 0.01 for vitamin d, which seems a decent enough proxy for lifestyle for this kind of study so your underlying point is valid here. Actually i think the biggest missing control is race.
I went in skeptical even though intuitively being deficient in vitamin d makes sense, this isn’t convincing but I agree with with their conclusion that it’s worth a bigger study.
If someone reading is wondering whether to maintain a healthy level of vitamin D to help if you get covid, yes you should. Should have done that before this study ofc.
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#4How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
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Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#5How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
There was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission.
This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation.
[1] https://www.sciencedirect.com/science/article/pii/S096007602...
[2] https://chrismasterjohnphd.com/covid-19/finally-confirmed-vi...
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#6How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
There was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission. This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation. [1] https://www.sciencedirect.com/science/article/pii/S096007602... [2] https://chrismasterjoh…
One should not leave out the important part "pilot study". As said by the authors in the conclusions themselves, it still requires a larger one to give definite answer.
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#7Earlier quoted context omitted.
There was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission. This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation. [1] https://www.sciencedirect.com/science/article/pii/S096007602... [2] https://chrismasterjoh…
One should not leave out the important part "pilot study". As said by the authors in the conclusions themselves, it still requires a larger one to give definite answer.
I agree that a larger N would be preferable, but the effect size was enormous, and so the P value was <.001. Therefore, IMO, it's very likely that Vitamin D has a causal effect. Given that Vitamin D has at least some causal effect, it's much more likely that the observational studies that show a correlation are due to causation.
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#8How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
They measure obesity and find it 0.02 vs 0.01 for vitamin d, which seems a decent enough proxy for lifestyle for this kind of study so your underlying point is valid here. Actually i think the biggest missing control is race. I went in skeptical even though intuitively being deficient in vitamin d makes sense, this isn’t convincing but I agree with with their conclusion that it’s worth a bigger study. If someone read…
Race can be a proxy for the amount of melatonin, which influences vitamin D. It can also be related to many other things. How would you use race to interpret the data?
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#9How do they net out the idea that people with healthy lifestyles would be less likely to have a vitamin D deficiency? (Better diet, more exposure to sunlight)
There was an actual randomized trial that came out recently [1] where hospitalized patients were given extremely large doses of Vitamin D (explanation of equvalent doses [2]) and it dramatically reduced ICU admission. This supports the idea that Vitamin D helping with COVID is probably causal rather than just a correlation. [1] https://www.sciencedirect.com/science/article/pii/S096007602... [2] https://chrismasterjoh…
I would be interested to know if supplementation with Vitamin D + Vitamin K2 is more effective in improving survivability.
Re: Vitamin D at least 30 ng/mL reduced risk for Covid-19 adverse outcomes
#10how much IU is this?