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Biohacking Lite

karpathy.github.io

1–10 of 370 posts

Re: Biohacking Lite

#4
> Clearly, my actual weight loss (red) turned out to be slower than expected one based on our simple deficit math (blue). So this is where things get interesting... so we don’t get to fully resolve the mystery of the slower-than-expected weight loss.

Weight loss is difficult and I think everyone, no matter how smart, dumb, famous or obscure they are, has trouble with it. It's always a surprise how difficult it is.

Re: Biohacking Lite

#5

As someone struggling to gain weight it always bugs me how "being healthy" is only associated with weight loss.

That's because, at least anecdotally, many more people are overweight than underweight, so "being healthy" involves weight loss more than weight gain.

Re: Biohacking Lite

#6
Unrelated but I just noticed `hydroxy-` (for ex: beta-hydroxybutyrate) means hydrogen + oxygen, whereas something like `hydro-` (for ex: hydrochloride) is just hydrogen. One of those obvious things you read all the time and not notice but obvious in retrospect.

Re: Biohacking Lite

#7

As someone struggling to gain weight it always bugs me how "being healthy" is only associated with weight loss.

My biggest concern about focus on weight loss as the metric instead of "healthy lifestyle" is that losing weight is easiest when you do it in an unhealthy way. Crash diets are a good example of unhealthy weight loss.

Another funfact is that you can literally go to bed for a few weeks, let muscle atrophy kick in, and lose more weight than any diet+exercise regime. Won't make you healthier, but you'll lose the weight. Yay metrics!

Re: Biohacking Lite

#8

As someone struggling to gain weight it always bugs me how "being healthy" is only associated with weight loss.

I think it is simply because a large number of adults in the US (as well as a lot of other countries) is struggling with this, at about 39% obesity rate and 71% overweight rate [0]. For comparison, only 1.5% of adults in the US are underweight [1].

While I agree that there is way more to "being healthy" than just not being overweight/underweight, I think it isn't a bad idea to approach this in the priority order. Solving the issue of being overweight is much simpler and much more impactful to the overall public health than trying to go after more rare and difficult problems.

0. https://www.cdc.gov/nchs/fastats/obesity-overweight.htm

1. https://www.cdc.gov/nchs/data/hestat/underweight_adult_15_16...

Re: Biohacking Lite

#9
> As a result I’ve improved a number of biomarkers (e.g. resting heart rate, resting blood glucose, strength, endurance, nutritional deficiencies, etc). I wish I could say I feel significantly better or sharper, but honestly I feel about the same. But the numbers tell me I’m supposed to be on a better path and I think I am content with that .

I appreciate this honesty

Re: Biohacking Lite

#10
post #5

As someone struggling to gain weight it always bugs me how "being healthy" is only associated with weight loss.

That's because, at least anecdotally, many more people are overweight than underweight, so "being healthy" involves weight loss more than weight gain.

Not only anecdotally, according to the CDC "prevalence of obesity was 42.4% in 2017~2018" in the US[1].

[1] https://www.cdc.gov/obesity/data/adult.html

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