Assuming you had enough resources in terms of google/aws/dropbox credit and free housing/internet.
Ask HN: If you could build any realistic project today, what would it be?
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Re: Ask HN: If you could build any realistic project today, what would it be?
#2Self hosted social networking and email platform that runs on Digital Ocean, OpenStack, etc. Total cost to user is around $5/mo hosting and $1/mo DNS for ad-free privacy-invasion-free Internet.
Ironic that you mention hosting resources, because in my view getting independent from those hosting services is itself the fundamental challenge.
Re: Ask HN: If you could build any realistic project today, what would it be?
#3Apply machine learning to the business of healthcare.
Re: Ask HN: If you could build any realistic project today, what would it be?
#4I would love to set up a workspace near an academic Institution, targeted towards bootstrapping people interdisciplinary careers. I would love for it to take applicants and then try to match them with contracts.