Cells edited using CRISPR–Cas9 injected into a person for the first time
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Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#2Here's a Kurzgesagt video about CRISPR for anyone that's curious: https://www.youtube.com/watch?v=jAhjPd4uNFY
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#3I was reading Oryx and Crake and I was thinking "There's no way this could happen... right?" then Trump said he basically wants to get rid of the FDA and EPA and now there's talk of a biomedical duel in human gene-editing?
Oh boy.
I can't wait to get a rakunk, myself.
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#4I was reading Oryx and Crake and I was thinking "There's no way this could happen... right?" then Trump said he basically wants to get rid of the FDA and EPA and now there's talk of a biomedical duel in human gene-editing? Oh boy. I can't wait to get a rakunk, myself.
With CRISPR, it's even better right; live gene editing. You can be a rakunk, rather than just own one!
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#5[deleted]
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#6> The hope is that, without PD-1, the edited cells will attack and defeat the cancer.
It seems that we already have good drugs which inhibit interaction between PD-1 and PD-L1 is there really enough benefit from this?
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#7I was reading Oryx and Crake and I was thinking "There's no way this could happen... right?" then Trump said he basically wants to get rid of the FDA and EPA and now there's talk of a biomedical duel in human gene-editing? Oh boy. I can't wait to get a rakunk, myself.
On a side note I read that book too & loved it.
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#8> The hope is that, without PD-1, the edited cells will attack and defeat the cancer. It seems that we already have good drugs which inhibit interaction between PD-1 and PD-L1 is there really enough benefit from this?
The effectiveness of drugs like pembro varies with cancer type and other factors. Here's a recent study where patients exhibited only a 56% response rate: http://www.nejm.org/doi/full/10.1056/NEJMoa1603702
The field is extremely promising and it's worth exploring fully, especially considering that even good responders can suffer relapses due to subclonal evolution.
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#9 I think the best (or worst?) part is that CRISPR can be used with a 'gene drive' it keeps the changes active on on-going it's not a one shot thing.
GATTACA?
Re: Cells edited using CRISPR–Cas9 injected into a person for the first time
#10I think the best (or worst?) part is that CRISPR can be used with a 'gene drive' it keeps the changes active on on-going it's not a one shot thing. GATTACA?
The "gene drive" - the quine of the genetic world.