First 'three person baby' born using new method
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Re: First 'three person baby' born using new method
#2Sounds like mother & father's nuclear DNA, injected into the nucleus of a 3rd party's donor's egg cell, which contains its own mitochondrial DNA. Since mtDNA is normally inherited 100% from the mother (since the mother's egg cell supplies the mitochondria to the embryo), if the mother has a mitochondrial genetic disease, 100% of her children would normally inherit it.
Re: First 'three person baby' born using new method
#3Additional background info from last year:
Re: First 'three person baby' born using new method
#4so science fiction of Alien Nation in a ways. so can they simply stock pile good genes and swap them out as necessary in the near future?
Re: First 'three person baby' born using new method
#5so science fiction of Alien Nation in a ways. so can they simply stock pile good genes and swap them out as necessary in the near future?
That strays into the eugenics region. Not there yet; the moral and legal 'obstacles' will be present for a long while.
Re: First 'three person baby' born using new method
#6[deleted]
Re: First 'three person baby' born using new method
#7mtDNA is also very significant in historical migration studies... if anyone has a high level explanation of the global state of knowledge in this area I would love to see it ... trying to author a regionally focused ancient history book and piecing together the disparate pieces of supposed genetic evidence for various things is a task I am wholly unqualified for and would love some assistance with.
Re: First 'three person baby' born using new method
#8Notably, this prevents transmission of a disease that is "fatal to any baby conceived", which makes this as uncontroversial a case of a "designer baby" as I can imagine. After this, the ethics get much more complicated.
Re: First 'three person baby' born using new method
#9mtDNA is also very significant in historical migration studies... if anyone has a high level explanation of the global state of knowledge in this area I would love to see it ... trying to author a regionally focused ancient history book and piecing together the disparate pieces of supposed genetic evidence for various things is a task I am wholly unqualified for and would love some assistance with.
This book did a great job, but it might be outdated:
https://www.amazon.com/Power-Sex-Suicide-Mitochondria-Meanin...
Re: First 'three person baby' born using new method
#10so science fiction of Alien Nation in a ways. so can they simply stock pile good genes and swap them out as necessary in the near future?
That strays into the eugenics region. Not there yet; the moral and legal 'obstacles' will be present for a long while.
I've never heard Eugenics defined in this way. I've only heard it used to mean selective planned breeding (as we do with livestock), but not intentional selective improvement of the parents' DNA.