Why do people put on differing amounts of weight?

Doing research on what people eat is VERY hard, it's very hard to get accurate data.

Pairing people and having them eat identically is brilliant. I hope it's also scalable for longer term studies.

By pairing people they are likely to give much more accurate reports about what they actually eat, and it allows direct comparisons.

(Note: "bad" and "good" above refers to "high-GI" and "low-GI", respectively.)

Another interesting anecdotal observation from my acquaintances: our relationships with food differ significantly. While some people simply like to eat (like myself - I find great pleasure in food and seemingly can't ever get enough), others simply don't find such enjoyment in eating - food tastes good for them, but not particularly amazing, and they don't seem to perceive the same amount of Freudian pleasure from the feeling of fullness. Interestingly, this seems to correlate highly (and again, anecdotally) with our life-long struggles with weight - the first group has to be conscious not to eat too much (and put on too much weight), while the second group consists of mainly skinny individuals, some of whom struggle putting on weight.

So the "goodness" and "badness" of food might have completely different base levels across population!

In a recent show one of the presenters (admittedly not Moseley) claims "The good news is that we have shown that Olive oil really is good for us", which was a ridiculous claim based on the evidence presented.

It would be a shame if that were excluded as a factor worth investigating, as research I've seen elsewhere indicates that it is [1].

The notion that the gut microbiome is a major factor in metabolism and health is now widely known and accepted, but it just raises the next question: what is the cause of variance in the health of the microbiome?

A good diet and supplementation with good microbes (probiotics, ferments, etc) is part of it, but the body itself also needs to do its part to create an environment that is fertile and hospitable for beneficial microbes, and inhospitable for harmful ones.

This requires a well-functioning immune system, correct enzyme activity, oxygenation, pH, optimal function of all the organs, to name just some of the factors in the vastly complex system that is the mammalian body.

Genetics and epigenetics play a key role in this system, and you'd hope to see this being included as a part of a study like this.

[1] https://www.geneticliteracyproject.org/2014/09/15/how-epigen...

I still remember the days when I could eat 3 - 4 pound of beef, along side with mesh potato, or 12 inch Pizza, or whole bucket ( 10pcs ) KFC, per meal! And these meals would come with Coke as well. in Tea time i will eat Ice Cream, eat lots of yogurt etc.

I dont do lots of sports, may be once a week maximum. Otherwise I just sit down playing World of Warcraft or watching TV.

All while I don't gain 1 pound of weight! I had a VERY hard time gaining weight when I was in the age of 16 - 22. I even tried those weight gainer and protein. And does't work

Now that i am a lot older, trying to lose some weight, I find out a lot of these theories simply don't make sense when i was younger. If you are what you eat, then I was definitely eating 4000+ calories per day and not getting Fat.

I think, everybody has a different body type that reacts differently.