Earlier quoted context omitted.
Until I see someone defining a representative example and running the numbers, I'm skeptical of their DC vs AC commentary. I say this, because I was guilty of this exact shortcut thinking (in another comment). But I paused and thought to myself "I should run the numbers before just repeating the usual voltage drop criticism". So I compared scenarios and it depends a lot on the topology, lengths, costs, and situation…
I'm skeptical of their DC vs AC commentary It's not about DC vs AC, it's high-voltage vs low-voltage. The power dissipation by wire resistance scales with the square of the current ($P=RI^2$), and low line voltage means that you need large currents to transmit the same amount of power.
But what about the sub 100W or even 200W applications? That's where I think something like 48VDC would start to shine. Every light in a home, phone chargers, tablet chargers, computer monitors, televisions, computers? (maybe not gaming rigs, but certainly laptops and nucs).