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Those with the most blame are the ones highest placed in our system who knew about and facilitated the smuggling, paying Americans along the way to assist, so that drugs could be located by anyone interested no matter where in this country they lived. They helped create the system that would lead to incarceration of people at the bottom of the ladder while those at the top who financed it all and benefited the most from it escape accountability. They created a network of small-town airports, private airstrips, and safe houses where distribution could be managed in a way that shielded the money people from the operations.
If you are a drug user, even a casual experimenter in your own home, your drug use continues to cause death and misery to uncounted other people and that makes you partly responsible for the societal destruction that drugs have wrought.