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Bird flu viruses are resistant to fever, making them a major threat to humans

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Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#92
post #88
post #72

Well, most humans (unlike me) take Tylenol even with a "fever" of just 38°C/100.5°F, so what difference does it make?

Unlike you?

I don't take any antipyretics, nor have I given to my kids, unless the fever is 39-39.5°C and climbing. Otherwise, you're sabotaging your own innate immune system!

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#94
post #72

Well, most humans (unlike me) take Tylenol even with a "fever" of just 38°C/100.5°F, so what difference does it make?

Unlike us, the virus will replicate much more quickly in their bodies. It wont kill them, but will likely make the infection last longer. Havent had a fever in many years, since taking flu and covid shots each year.

Well, if you let your innate immune system do its job, fever can actually kill many pathogens and also ramp up your immune system response. It's fascinating that human cells can survive at slightly higher temperatures than most pathogens, giving us an advantage. It's not comfortable to have a high fever, and there's a slight chance of kids getting febrile seizures (although most are not actually that bad), but we do more harm ot ourselves for little comfort or a complete lack of soicism.

I get headaches sometimes. I know 200mg of ibuprofen can help me, but I chose not to. Pain is part of reality. If we mask it, we have little incentive to address the root cause.

I had COVID-19 in August this year. I had a 39.5°C fever for 2 days, then it subsided for 7-8 more days - I didn't take any antipyretic. You know, you can actually tolerate it if you accept it as something normal. And it's also a great experience to actually learn to know when you have a fever - you don't need a thermometer even.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#96

Earlier quoted context omitted.

He said that.

Fever isn't just a symptom. It's a defense mechanism. The idea is that use of antipyretic drugs may make the infection worse.

The sentence is constructed, weirdly, but it's meant to say that fever is "killing off unknown foreign bodies"

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#97

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

You want your immune system to simmer, not to boil.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#98

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

I know someone who doesn't get fever. When he gets sick with regular cold or fly it's much longer and worse than for anyone else I know.

You usually don't get a fever from a cold (except in Japanese anime), if there's a significant fever it's more likely to be a flu. Or, these days, could be Covid.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#99
post #94

Earlier quoted context omitted.

Unlike us, the virus will replicate much more quickly in their bodies. It wont kill them, but will likely make the infection last longer. Havent had a fever in many years, since taking flu and covid shots each year.

Well, if you let your innate immune system do its job, fever can actually kill many pathogens and also ramp up your immune system response. It's fascinating that human cells can survive at slightly higher temperatures than most pathogens, giving us an advantage. It's not comfortable to have a high fever, and there's a slight chance of kids getting febrile seizures (although most are not actually that bad), but we do…

Pyrotherapy. The idea of fighting untreatable (at the time) illnesses by inducing a fever in the patient. There's actually a Wikipedia article about it: https://en.wikipedia.org/wiki/Pyrotherapy As in deliberately infect a syphilis patient with malaria, which can give you a very high fever. The first time I heard about that one was in Neal Stephenson's Baroque Cycle, turns out it was one of the non-fictional parts of the books (which were a mix of historical facts and fiction).

Quote: "In general, the body temperature was maintained at 41 °C (105 °F).[1] Many diseases were treated by this method in the first half of the 20th century."

The malaria variant was not the common variant, that was saved for extreme cases, apparently (e.g. Syphilis). Mostly it was hot baths and the like.

I, for one, will stick to my near-daily sauna sessions.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#100

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

It's a fairly common notion to "sweat out" a flu. Stay in bed, wrap yourself up in lots of blankets and just sweat the damn thing out. High body heat kills the virus.

So it would make sense that drugs like tylenol/paracetamol would make you feel better, but would keep the flu alive in you for longer.

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