Loss of crew tolerance is not what it used to be. The Apollo astronauts were given about a 10% chance of not coming back. In Apollo 13 they very narrowly avoided. Which was considered acceptable for the time period. I'd argue that mission failure tolerance is also considerably lower, in todays political environment. Again, Armstrong said their chances of actually landing were maybe 50/50. So if they get there and hav…
The Shuttle towards the end of its life had an estimated chance of loss of crew of 1 in 90, and two administrations decided that was untenable. The standard for missions to ISS is 1:250. If a goal of Artemis is to meet modern safety standards, it's falling way short.