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Cheap antidepressant shows promise treating early Covid-19

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Re: Cheap antidepressant shows promise treating early Covid-19

#91

Post by tokai »

trevorishere wrote: post #89
wnkrshm wrote: post #60

Earlier quoted context omitted.

Are they really? As someone who takes SSRIs after trying out more 'serious' alternatives for ADHD-related depression (e.g. slow release stims which are bona-fide narcotics), SSRIs are treated like candy and the first treatment option it seems to me.

SSRIs can induce undiagnosed Bipolar or SSRI-induced Bipolar disorder; in certain cases with rapid cycle. It’s not fun.

Only if you have it underlying already. And in that case it can be triggered by stress, lack of sleep, etc.

Re: Cheap antidepressant shows promise treating early Covid-19

#92

Post by vixen99 »

jollybean wrote: post #69
6nf wrote: post #65

Earlier quoted context omitted.

Ivermectin is approved for covid use in the UK and many other countries with good results and a large Oxford study is close to completion to add to the dozens of positive studies

No. " Ivermectin is currently not approved in the UK for the prophylaxis or treatment of COVID-19," [1] There are no good studies demonstrating the validity of Ivermectin, and the Oxford study is not complete and there's no indication results are positive. Why are people so crazy about this drug? It doesn't look like it works, though there is some possibility it will, but we'll only know when the Oxford trial is comp…

If 'good' is synonymous with double blind randomized studies then an awful lot of drugs used for decades don't meet that requirement. When you're anonymous it's better not to be too assertive on these questions. Aside from the DBR definition, are you able to authoritively review hundreds of studies on ivermectin?

Re: Cheap antidepressant shows promise treating early Covid-19

#93

Post by shapefrog »

sdhfjg wrote: post #81
nuerow wrote: post #74

Earlier quoted context omitted.

> When a medical doctor prescribes a drug for a purpose that is currently being studied scientifically, that is not "alternative medicine". It really is, as there is absolutely no evidence it has any effect whatsoever and at best it only serves as a placebo. In short, it's snake oil. Worse: politically-motivated snake oil.

Are the people participating in the scientific studies of the drug participating in alternative medicine?

Define: alternative medicines

Complementary and alternative medicines (CAMs) are treatments that fall outside of mainstream healthcare.

> Are the people participating in the scientific studies of the drug participating in alternative medicine?

Well the placebo group taking sugar pills for their cancer are not exactly going 'by the book' or lamestream healthcare and the active group taking whatever ... well lets just agree to disagree shall we?

Re: Cheap antidepressant shows promise treating early Covid-19

#94

Post by m0zg »

DantesKite wrote: post #62
_ywdj wrote: post #44

From my own experience I can very much believe an SSRI could have an effect on the immune system and/or the respiratory system. I was a heavy cigarette smoker in my 20s, and over those years, I experienced worsening asthma and also worsening anxiety and depression. Eventually I was prescribed an SSRI (Zoloft), and found that not only did my mood change, my asthma completely abated, even though I was still smoking jus…

If you continue having issues, consider taking NAC. It's very commonly used to treat bronchitis and my asthmatic mother has had tremendous success with it.

FDA banned OTC NAC sales after it found out it might help with COVID [1]. Can't have that. And yeah, I know you're suggesting it for something else, but it's hard to get now.

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7649937/

Re: Cheap antidepressant shows promise treating early Covid-19

#95

Post by toomanybeersies »

_huayra_ wrote: post #45
woodruffw wrote: post #10

Earlier quoted context omitted.

SSRIs are pretty serious, which is why you should probably just get vaccinated instead.

It's so strange how people are looking to truly foreign substances / drugs (from ivermectin to bleach to SSRIs now) compared to a vaccine, which is basically just a bunch of mRNA and a few preservatives. That is, a bunch of stuff that is basically already floating around in our bodies / cells.

Why not both? Vaccination isn't a silver bullet.

Re: Cheap antidepressant shows promise treating early Covid-19

#96

Post by weird-eye-issue »

m0zg wrote: post #15

I bet with crystal meth you won't even notice your COVID if you take enough of it. Not sure it's a worthwhile tradeoff though, though I'm sure "legalize everything" crowd would disagree. Taking SSRIs to very marginally reduce severity seems like an extremely dumb idea.

Did you just compare crystal meth with SSRIs?

Re: Cheap antidepressant shows promise treating early Covid-19

#98

Post by throaway46546 »

_huayra_ wrote: post #45
woodruffw wrote: post #10

Earlier quoted context omitted.

SSRIs are pretty serious, which is why you should probably just get vaccinated instead.

It's so strange how people are looking to truly foreign substances / drugs (from ivermectin to bleach to SSRIs now) compared to a vaccine, which is basically just a bunch of mRNA and a few preservatives. That is, a bunch of stuff that is basically already floating around in our bodies / cells.

Vaccinated people still get sick and die from covid. It isn't the end all be all. We still need effective treatments.

Re: Cheap antidepressant shows promise treating early Covid-19

#99

Post by deepnotderp »

rscho wrote: post #64

This thread has the strongest 'pseudoexpert-statistical-bro' vibe I ever experienced. It's amazing! You can have your own beliefs regarding COVID, but it surely revealed a lot about the social perception of statistics... #-/

As opposed to "experts" who always have rock solid statistical knowledge (/s): https://stats.stackexchange.com/questions/38403/what-causes-...

https://en.wikipedia.org/wiki/Misuse_of_p-values

I wish that people would stop disparaging attempts to contribute from people outside the specialized ingroup.

This stuff is hard, what counts as a hypothesis test for instance? Should datasets be locked and each view counted as a hypothesis? That's a very reasonable debate.

Re: Cheap antidepressant shows promise treating early Covid-19

#100

Post by shapefrog »

z80x86 wrote: post #17
blinkingled wrote: post #5

> In the group that took the drug, 11% needed hospitalization or an extended ER stay, compared to 16% of those on dummy pills. Is that really promising? Very close to margin of error if not within.

> A cheap antidepressant reduced the need for hospitalization among high-risk adults with COVID-19 in a study hunting for existing drugs that could be repurposed to treat coronavirus. You’re right to be suspicious; data dredging 101.

Astham went from being a risk factor to a risk reduction factor. Smoking likewise, we are even at the point where One study suggests this could be because nicotine interferes with ACE2 receptors, which may prevent the virus from entering cells.

Why isnt everyone having a cigarette each day to interfere with the ACE2 receptors?

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