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Sacklers–who made $11B off opioid crisis–to pay $225M in damages

arstechnica.com

91–100 of 109 posts

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#91
Since this will inevitably turn to a discussion of opioids, here are some counter-narrative facts that surprised me:

1. The narrative is that some poor guy took pain meds for a legimate reason then ended up addicted. While this does occur, it's actually not very common.

> Among people who are prescribed opioids, addiction is relatively uncommon. The percentage of patients who become addicted after taking opioids for chronic pain is measured in the single digits; studies show an incidence from less than 1 percent to 8 percent. Most of the estimates are skewed toward the low end of this range, when those at risk (due to a history of substance abuse or, to a lesser but meaningful extent, a concurrent mental illness) are removed from the sample.

2. Most addicts had a history of drug abuse.

> People who abuse pills are rarely new to drugs. The federal government’s 2014 National Survey on Drug Use and Health, for example, revealed that more than three-fourths of misusers had used non-prescribed benzodiazepines, such as Valium or Xanax, or inhalants. A study of Oxycontin users in treatment found that they “were not naive individuals with accidental addictions who were introduced to painkillers by their physicians as reported by the media … [Instead they had] extensive drug use histories.”

It's hard to bring this up without straying into classism or victim blaming. The reality is that most people without comorbidities and abuse history are quite safe, and these are drugs we need.

[1] https://www.theatlantic.com/ideas/archive/2019/08/what-ameri...

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#92
post #17

The Sacklers engaged in unethical behavior to get people hooked on something that made them money. Easy opioid prescriptions created thousands of (mostly) functional addicts who were getting their fix in a high-quality control form via their doctor on a monthly basis. That's bad but that's not an opioid "crisis". You don't get a crisis because of a few evil billionaires. More things have to go wrong. What really turn…

So since the market created functional drug addicts that’s ok and the government caused the problem by trying to stop the market from creating drug addiction?

The government showed up to a grease fire and poured water on it. They're in the murky area where incompetence, negligence and malice meet.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#93
post #76

Earlier quoted context omitted.

It's tricky to meaningfully separate these cases, as many opioid addictions start with prescriptions and move to more available opioids when the prescriptions end.

This is substantially less common than is widely believed.

This varies a lot by area, but it isn't rare.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#94

Earlier quoted context omitted.

Start by reforming the justice system. It is badly broken at all levels. It's slow speed, incredibly expensive interactions, and hard-to-understand system of laws need a big time upgrade. We need relatively simple laws that ordinary folks can understand, and a much faster time-to-judgement. It is really the complexity and cost of the system that leads to so many of these unjust outcomes, because hardly any actors in…

Justice cannot happen without input from the those who are on the other side, the indicted. You quickly realize justice TRIES to be a really bad cop. And then the indicted /convicted have to make deals for something that is terribly unfair. Just imagine negotiating with a person like Kamala. When I see light weight no benefit deals like this, I think that it looks like both prosecutor and defendant got away with murd…

This is all true, but I think its a symptom of a more fundamental problem, which is the complexity of the system, and the attendant speed and cost problems that drive agents to these outcomes. If the system worked transparently and quickly, then a lot of the other problems would go away. Plea deals should be the exception, not the rule.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#95
post #82

Earlier quoted context omitted.

We really have to stop letting wealthy people and corporations buy their way out of legal problems. Fines and settlements clearly don't stop bad behavior as banks and polluters have been showing repeatedly. The whole thing feels like a protection racket where it's ok to do illegal stuff as long as the government gets its cut. Either somebody has to go to jail or the fines have to be on a level that they lose all of t…

Seriously. This still leaves the door open for the next drug crisis to make a (literal) killing and get a slap on the wrist in ten years. What's next? I wouldn't be surprised if Pfizer started pushing Xanax and other benzodiazepines as a way to tie patients over while they wait the 2-6 weeks from talking to their PCP for a psychiatry referral and actually seeing a therapist.

The Benzo crisis is already here.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#96
post #30

Earlier quoted context omitted.

As someone who uses both (irregularly, only as necessary), legal thc / CBD doesn't even remotely compare. I have to get so high to even approximate the pain relief from an opioid that I'm completely nonfunctional. I had my first back surgery at 18, my second at 25, and I've been staving off 5 separate herniated discs since. I'm in a good place now (barring literally today), but I can't stress enough how useless you e…

Just a warning, Tramadol reacts very badly in some people. Like myself, just a single pill will cause me to have tonic-clonic seizures leading up to a grand-mal seizure later on in the day. Tramadol also has a bunch of shit in it, I feel like it's a 'dirty' drug. For example, it's very closely related to the chemical structures of antidepressants. This can be helpful, but not when you need to stop it. You also can't…

As someone who takes tramadol daily, and has done for about 7 years, I respect that it isn't the best option. But right now I don't have better alternatives. Yes, I've taken breaks for up to a month (without needing to ween, never upped my dosage).

Cannabis doesn't work. Paracetamol/acetaminophen, ibuprofen, NSAID's don't work.

Morphine, codeine and tramadol do. Tramadol is the best of a bad bunch.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#97

I know everybody loves to hate on the Sacklers, but my life was dramatically better when I had access to opioids. Because of the "crisis" it has gotten really difficult to get them, even for people who need them. There are days when it's difficult to do much more than lie in bed in agony, but nobody beyond a small community of other pain sufferers seems to care. I'm at least grateful for the few good years I did get…

Apparently your pain and suffering is less important than getting the Sacklers.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#98
For reference, this is ~7.5 cents per prescription given out in the US from 2006 to 2018.

I've no idea how to break that down into a per pill basis, but it's likely to be much less than a cent per pill.

I very much doubt that the Sacklers profited less than a cent per pill though.

https://www.cdc.gov/drugoverdose/maps/rxrate-maps.html

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#99

Earlier quoted context omitted.

I hear what you're saying, but it feels like you should be placing your blame on the sacklers too - if they hadn't pushed opioids on people who didn't need them, fueling the crisis, then there would not have been this backlash you describe. Like, we shouldn't be mad at opioids, we should be mad at drug pushing profiteers.

That's a reasonable point, although if they hadn't helped make doctors more comfortable with using them, then I may not have ever gotten them in the first place as they would be stingy with them like they are now. Hard to know where I would have landed.

The Sacklers lied to doctors and told them that OxyContin wasn’t addictive. They and their henchmen should be strapped to a gurney and sent off with a IV drip of OxyContin.

Re: Sacklers–who made $11B off opioid crisis–to pay $225M in damages

#100
post #4

In their defense, they really wanted make a ton of money, really didn't want to pay a huge fine. So, you know, it all kind of worked out. For them.

You’re being sarcastic, in their defense, right?

I'm not sure I was sarcastic so much as I was bitterly cynical.
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