I built a similar little machine a couple years ago, mostly for storing my big archived files, being a borg backup target for my other machines, and subsequently mirroring said backups offsite with rclone.
I went for a Chenbro SR301 case (I don't know what's changed in the still-available SR301 Plus model) + modest commodity parts over the HP or Supermicro turnkey boxes in a similar form-factor mostly because it takes standard components (mini-ITX boards, ATX PSU, standard fans... nothing I couldn't overnight from any major vendor for cheap) for easy replacement. It was also a little cheaper.
I did btrfs "RAID10" instead of RAID. Hardware RAID is always a hassle, btrfs is in-kernel, and it has all the nice modern data integrity features (two spindle rule, I have a timer that scrubs it periodically for to verify checksums, etc.) - I've been really pleased with that except for the lack of good automated monitoring/notification tools for btrfs.
Documentation I wrote at the time, more about the backup scheme than the machine at https://pappp.net/?p=1627
I'm still using that setup, eventually I'll need to swap some discs as capacities increase, but that machine has required zero fucking around since it was set up.