I see this as an argument in favor of native apps. I mean really native, not Electron-esque ones. As you more and more turn the browser into an OS, you have to treat it like an OS. Don't allow unprivileged user to install unsigned kernel modules.
And then on the web, you just load pages. Pages are pages, except ones that come over https get Special Privileges because the Chrome team decided that was the best way to decide whether user content could be trusted. And pages that load from the local filesystem are less trusted, because it's only safe if it's coming through a socket. Any content hosted on a given domain is just as trustworthy as other content on that domain, and most importantly - very importantly - if the end user installs an extension, it's very essential that the extension be able to easily exfiltrate every single byte of your gmail inbox. After all, pages are pages - why should gmail or my bank be special compared to any other website?
Nobody put any real thought into how to structure the permissions model to combat real security threats. WebExtensions (the de-facto Worse is Better standard) basically dumps a bunch of different features into the 'do anything' permission bucket and leaves it up to the user to decide whether to trust an extension, despite the fact that an extension's ownership can change at any time. If an extension starts out without requesting any permissions, requesting a new permission (to do something useful) will silently disable your extension for all your customers - so naturally, what people do is request every single permission from the beginning, and users click Install anyway.
It's positively grotesque that the warning for this is still "read and change all your data on the websites you visit", and that so many trivial things require it. Chrome still makes no effort to draw your attention to how very, very dangerous this permission is. Say what you will about the UAC trainwreck but at least the SmartScreen 'this software is suspect' popups are suitably scary Red or Yellow and large, legible text.