Earlier quoted context omitted.
> I found out a year later that it dramatically affected my personality. More or less like in the article, but in the opposite way. So the blood pressure medication made you more calm? You didn’t specify the medication they prescribed, but that’s a common effect of certain types of blood pressure medication. In fact, certain blood pressure medications are prescribed off-label for their calming properties. One blood p…
Blood pressure medicine does make you more calm and this is known anecdotally among the medical community. I know this because I know of medical students taking it before giving a speech. Literally the medicine is well known for making you perfectly calm. You know that magic pill that can get rid of your approach anxiety? I hear, this is it, though I never tried. I'm wondering if anyone more in the "know" can comment…
Medications that change who we are
91–100 of 289 posts
Re: Medications that change who we are
#92>"It turns out many ordinary medications don’t just affect our bodies – they affect our brains." I feel like perpetuating this mindset is the ultimate sin of modern psychiatry and the entire industry of psychiatric pharmaceuticals - your brain is your body. It's not some special thing that sits apart from it. It is an integral part of the whole, no different than your kidneys or liver. People think they can take an a…
Even if the brain is not apart from the rest of the body, there is a special thing between the two: the blood-brain barrier, which is actually quite hard to cross with medications, and poses a real challange in curing brain diseases.
And even if they didn’t, the body is a tightly interconnected system. Taking an antidepressant to “selectively affect serotonin” in the brain? Whoops, turns out your gut has at least as many serotonin receptors as the brain. Taking a statin to reduce cholesterol (which it does very well but with an NNT > 200 for heart attacks and NNT > 300 for stroke)? Whoops, it causes transient global amnesia and personality changes and diabetes in a lot of people. And 40% of the US Adult population we’re on statins in the mid 2000s.
Re: Medications that change who we are
#93Earlier quoted context omitted.
I think the problem goes at least as far back as Plato and the allegory of the cave. Plato spread this concept that there was a difference between the body and mind or soul, and Western culture has never really recovered from the stupidity of that idea. There's really no evidence or justification for it. Your mind and your body are the same thing.
Modern philosophical thought and religion were built on that idea, and they were arguably inextricable from science in it's early stages. This is like someone people never fully recover from adolescence. Correct, it forms an integral part of who you eventually become.
So were lots of bad ideas. Science is a process of trial and error. This was an error. The hope is that you correct the errors, not make them an integral part of your belief system.
Re: Medications that change who we are
#94Earlier quoted context omitted.
I think the problem goes at least as far back as Plato and the allegory of the cave. Plato spread this concept that there was a difference between the body and mind or soul, and Western culture has never really recovered from the stupidity of that idea. There's really no evidence or justification for it. Your mind and your body are the same thing.
I believe the mind, or soul, is indeed in the brain. But it's also separate. It's more like software controlling the hardware. Take self control and attention. How many people struggle with it, procrastinating? You want to do something, you know you have to do it, you like doing it... But you don't. Because your brain doesn't listen to your mind. Because the brain is mostly a primitive autonomous system and needs to…
Yes, that's correct, and I really don't understand what you think you've said that proves otherwise.
Re: Medications that change who we are
#95I had never heard of this link between statins and aggression and Tylenol and lack of empathy before. Interesting. Maybe this is why Boomers act so strange now. “Former flower children lost their empathy and caring for the world and the next generation when their doctors put them all on statins and they started gobbling Tylenol” would be quite an interesting story. Both my parents are on statins, it seems every perso…
In my experience, modern doctors are well aware of the risks of statin treatment. I'm sure you can find trigger-happy doctors who over prescribe statins, but that's definitely not the recommended best practices.
According to one of the first studies I found, only about 1 in 4 patients who fit the criteria for statin use are actually prescribed statin medications at followup: https://www.ahajournals.org/doi/full/10.1161/JAHA.118.010241
Re: Medications that change who we are
#96I have long wondered about this. In the Asian world, traditional Systems of Medicine focus on "holistic" treatment and the general public often calls Western Medicine, "Allopathy with side-effects". I had intuitively felt that these medicines must have an overall effect on behaviour which may always not be obvious to the observer unless the difference between the before and after were stark and noticeable. We really…
[rant on]
I believe the term you’re looking for here is “fabulist bullshit”.
“the general public often calls Western Medicine, "Allopathy with side-effects"”
Aaaand… No, it doesn’t. SCAM calls it that. Which is ironic, as “Allopathy” is a term coined by Hahnemann to mean “Everything BUT Homeopathy”, and that was in a day when “Western Medicine” was itself rank quackery still laboring under Galen’s “Four Humors” nonsense. Thus Chiropracty, Reiki, TCM, Acupuncture, etc are all “Allopathy” too.
Conversely, what you so casually misnomer “Western Medicine” (the term itself is borderline racist) is just “Medicine That Works†”.
(†“Within Limits”, as any sci fule kno.)
I mean, the only really significant difference between Traditional Chinese Medicine’s explanation of disease and Galen’s is that TCM believes in five humors while Galenites believed in only four. [Insert Emo Philips/Picard joke here.]
Otherwise “Chinese/Eastern Medicine” is the same mix of ungrounded herbalism and bloodletting that stalled out western healthcare for 2000 years. Until the Arab/Persian world, during its all-to-brief scientific golden age, came up with the brilliant idea that one should actually test one’s beliefs to find out if they’re bullshit or not… a process that Renaissance Europe finally distilled into modern scientific method 500 years later and determining Galen was full of it shortly after that.
..
Of course, getting the actual institutions to change took a lot longer; it wasn’t until Pasteur gave us a working model of disease that Galen’s bollocks and its attendant “worse than doing nothing at all” so-called treatments were finally buried down a very deep hole.
Germ Theory gave us sanitation, vaccination, and surgical hygene. Untested herbalism was usurped by pharmacognosy, modern chemistry, and reliable mass manufacturing. And so on.
Alas, China was been quite so lucky. Thanks to Mao and his vast “barefoot doctor” scam (which got around the problem of not having enough real doctors or money to provide everyone else with medicine that worked), TCM/Acupuncture is still around, not least as the CPC is now selling it for export as much as for use at home.
Incidentally, Mao himself (like most wealthier Chinese nowadays) had no truck with that homegrown crap and happily availed himself of your “Western Medicine”, thankyouverymuch. (You might want to take note of that.)
Incidentally #2, just as TCM was, and is, badly-tested herbalism marketing often poor-quality and fraudulent product, pre-Mao acupuncture was really just Galenic-style bloodletting sticking bloody great bamboo trocars into people. Worse, it had almost (rightly) died out until Mao reinvented it its modern form using fine steel needles, bad sterile practice, and total Qi bollox. “Distracting the patient while nature all does the work” as Voltaire used to say.
Incidentally #3—and considering that western researchers invested decades in figuring out how to reliably blind acupuncture studies before finally producing results showing it no better than placebo—every acupuncture study out of China is still positively glowing. Someone recently posted a FP link regarding China’s massive ongoing medical research crisis; I’m sure you can dig it up if you want.
..
TL;DR: You can take your “holistic treatment” and “traditional Systems of Medicine” and stick ’em where the pathologist’s light does shine, because that is where they all belong.
[rant off]
--
Real medicine does in fact study and treat the whole person. Unfortunately, it’s also a victim of its own and industrial nations’ success. General practices and hospitals are slammed with demand, increasingly with inevitable diseases of very old age (since so few of us die young now) and diseases of sedentary urban lifestyles.
And while doctors can tell us to eat less and exercise more till they’re blue in the face, they can’t make any of us do it; so it’s not surprising things like statins get widely (over?) prescribed as a workaround for our fat lazy butts.
I’ve no doubt too modern medicine desperately wishes more public would understand that all Medicines (that is, pharmacologically-active compounds) have multiple Effects; and that the only meaningful distinction is between Effects that are advantageous in treating a patient for a particular condition and Effects that are disadvantageous in that same patient. We commonly call the latter “side-effects” [not counting intolerance and allergies], but that’s misleading.
For instance, aspirin (descended from willow bark) is commonly used both as an NSAID and as an anticoagulant; thus what is a “side-effect” in pain patients is the therapy in those with blood disorders. (And vice-versa. And, of course, aspirin’s other common effect of giving you stomach ulcers isn’t a benefit in anyone. Although if you think aspirin is bad, just try original willow bark instead.)
Thus, we should not be surprised that modern pharmaceuticals have multiple effects across a wide range of biochemical and physiological systems; if anything, it’s a minor miracle they don’t have way more unwanted effects. Alas, familiarty does breed laxness, if not contempt, even in scientific and medical professionals; so it can never be re-stated enough that education, awareness, and due dilligence are essential to keeping that system operating as well as it can.
Think of it like this: Medicine [which works] is just a rolling bug-patching process of the most heinously complicated, tightly-coupled, under-documented Big Ball Of Mud known to man, and proceed accordingly. And that even that thing we call “self” is just a synthesized fiction, the product of countless biochemical and electrical interactions constantly occurring in just one[-ish] of numerous intricately interconnected organs, which together make up “Us”.
--
Dear Dog, I really need a drink now. Never been so glad I that crashed out of premed and landed up in software dev instead. :)
Re: Medications that change who we are
#97As I get older I began to think the opposite; that our thoughts, personalities, and everything original about us are a product of our physical composition and brain structure.
I began to really notice this after reading Principles where Ray Dalio observes that the way people think and approach and solve problems are largely fixed. I notice this in myself and the people around me.
There was a sort of inflection point for me after getting my first massage. My body was completely relaxed, resulting in my mind being completely relaxed. After the massage I went to a trader joes in columbia maryland during a saturday. This trader joes is a logistic nightmare that always stresses me out, so much so that I would usually avoid going during peak shopping. But this time I was completely unbothered, nothing about the experience was bothering, my thoughts were completely at ease. At that moment I realized that it wasn't stress making me tight, it was tightness making me stressed. The dependency was completely backwards from the way I thought. Being self centered i thought my thoughts informing my physical, but it was actually my physical causing my thoughts.
I have genetically high blood pressure, and I have to consume low sodium in order to keep it under control. While I was learning this and my blood pressure was high, I was literally angry about everything. Road rage, meltdowns at home, being short and explosive with my wife and son. I thought it was stress or affect from work I thought it was thoughts/personality -> body. As soon as I experimented with reducing sodium, getting exercise and my blood pressure dropped, my mood completely rounded out and fixed itself. IT was actually my body -> thoughts.
The same thing happens with hiking spending time outside. I used to feel like a connected, or spiritual relationship with the outdoors. I enjoyed drinking and camping, I thought that there was a spiritual relationship with the outdoors (personality -> body) when, once again, it's actually just physical -> personality, dopamine is released, my blood pressure probably dropped my thoughts became more relaxed, my body was tired and relaxed from hiking.
I think that we really are a lot less conscious than we think we are, and that the way we think, our personalities, and pretty much everything about us is largely predetermined by our physical composition. I think we're just more complicated animals and our personalities are just a response to physical input and reactions.
Re: Medications that change who we are
#98I have long wondered about this. In the Asian world, traditional Systems of Medicine focus on "holistic" treatment and the general public often calls Western Medicine, "Allopathy with side-effects". I had intuitively felt that these medicines must have an overall effect on behaviour which may always not be obvious to the observer unless the difference between the before and after were stark and noticeable. We really…
“In the Asian world, traditional Systems of Medicine focus on "holistic" treatment” [rant on] I believe the term you’re looking for here is “fabulist bullshit”. “the general public often calls Western Medicine, "Allopathy with side-effects"” Aaaand… No, it doesn’t. SCAM calls it that. Which is ironic, as “Allopathy” is a term coined by Hahnemann to mean “Everything BUT Homeopathy”, and that was in a day when “Western…
https://archive.org/details/thirtyyearsinmo00chrigoog
Written by this fellow:
Re: Medications that change who we are
#99Earlier quoted context omitted.
I think the problem goes at least as far back as Plato and the allegory of the cave. Plato spread this concept that there was a difference between the body and mind or soul, and Western culture has never really recovered from the stupidity of that idea. There's really no evidence or justification for it. Your mind and your body are the same thing.
Plato's allegory of the Cave is about the liberation provided by education, and self-awareness. How gaining understanding of your environment freed you from the limited reality it presented you. The initial usage of the story was to illustrate how political indoctrination could present a false reality to ardent followers "the shadows of cave fire for those raised in the cave", and how education could "open the eyes a…
Consider the analogy "arms are like wings". That's actually true in a lot of ways, but we can't simply assume that arms have all the properties of wings by analogy, otherwise we'd conclude that arms allow us to fly.
That education improves our capabilities is fairly well proven via other means.
Re: Medications that change who we are
#100>"It turns out many ordinary medications don’t just affect our bodies – they affect our brains." I feel like perpetuating this mindset is the ultimate sin of modern psychiatry and the entire industry of psychiatric pharmaceuticals - your brain is your body. It's not some special thing that sits apart from it. It is an integral part of the whole, no different than your kidneys or liver. People think they can take an a…
O-kaaaay.
But, as the science kids all say:
[Citation required]
(Please note Scopie’s Law is now in full effect.)