If you're on a Mac, try tmux -CC with iTerm2. You get tmux goodness like multiple panes, persistent sessions, etc. But you also get native scrolling, native copy and paste, etc. It's what makes tmux usable for me.
Absolutely! TMux is pretty great by itself, but it doing its own internal scrolling and copy-pasting, though essential, is a usability frustration. Tmux + iTerm2 is a fantastic combo that takes all of Tmux's pwer and removes all the downsides. I searched if anything else used Tmux's Control Channel on Linux to replicate iTerm2's features, and I'm sad that I found nothing. (Frankly, it's kind of stunning to me that on…
Such an enormously usable thing, why isn't that readily available on Linux?