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Puzzle-solving 'doesn't slow down mental decline in older people'

nhs.uk

91–100 of 111 posts

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#91

FWIW, I told a good friend to get her dementia-diagnosed father on a schedule of daily Dual N-Back training using open source programs (e.g. Brainworkshop). She asked his neurologist how effective this would be and he basically said, "it's the only cognitive training that could do anything." Not only is Dual N-Back a great mental workout, but it will also put you to sleep pretty quickly if you set the parameters such…

BTW what is the definition of "'randomness' factor or level of pattern obscurity"?

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#92
post #50

Earlier quoted context omitted.

15 -years- is a LONG time for a study. I'm not sure about the dropout rates, but it is a real statistical issue. I'm just not sure there's anything that can reasonably be done about it. You'd have to have something like federally mandated participation / continued participation. That's also very unlikely to pass ethics boards. BTW, it would also be an issue if the subjects were compensated to the point that they diff…

15 -years- is a LONG time for a study. I'm not sure about the dropout rates, but it is a real statistical issue. I'm just not sure there's anything that can reasonably be done about it. Everyone keeps replying as if my comments imply a demand that "something be done about this". That's not my point. Maybe nothing can be done about it. The situation is still significant or at least appears significant.

Similarly, it may be that running studies like this is really difficult and that massively reduced sample sizes are something we must accept for practical reasons... but that doesn’t mean it permits us to ignore statistical ramifications

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#93
I really liked the shared article.

In contast to what other news sources publish, this article links the original paper, reviews the metodology, gives some introductory explanations on the subject and provides all sorts of 'further reading' resources.

Really enjoyed it, thanks for sharing!

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#94
post #67

FWIW, I told a good friend to get her dementia-diagnosed father on a schedule of daily Dual N-Back training using open source programs (e.g. Brainworkshop). She asked his neurologist how effective this would be and he basically said, "it's the only cognitive training that could do anything." Not only is Dual N-Back a great mental workout, but it will also put you to sleep pretty quickly if you set the parameters such…

That seems like quite a strong claim. This would need to be supported by extraordinary empirical evidence. It's rather difficult for us to independently verify your friend's neurologist's word. Do you perhaps have some scientific studies to hand which might demonstrate the efficacy of this treatment?

My claim is only that a single neurologist said if any cognitive training might help, then N-Back training would be it. I have no other evidence other than my friend's testimony. Say the neurologist did say this, what's the implication? That you have defeasible justification for trying N-Back training, on recently diagnosed dementia patients, if you've already made the decision that cognitive training is worth pursuing (along with other treatments).

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#95

FWIW, I told a good friend to get her dementia-diagnosed father on a schedule of daily Dual N-Back training using open source programs (e.g. Brainworkshop). She asked his neurologist how effective this would be and he basically said, "it's the only cognitive training that could do anything." Not only is Dual N-Back a great mental workout, but it will also put you to sleep pretty quickly if you set the parameters such…

Is there any scientific evidence behind "the real benefits come when you get (2) maxed out while keeping an N-Back of 3"? Sounds really curious to know.

Nothing but a small set of scattered anecdotal evidence from people in the N-Back community. I would be interested in an actual study on this.

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#96
post #67

Earlier quoted context omitted.

That seems like quite a strong claim. This would need to be supported by extraordinary empirical evidence. It's rather difficult for us to independently verify your friend's neurologist's word. Do you perhaps have some scientific studies to hand which might demonstrate the efficacy of this treatment?

My claim is only that a single neurologist said if any cognitive training might help, then N-Back training would be it. I have no other evidence other than my friend's testimony. Say the neurologist did say this, what's the implication? That you have defeasible justification for trying N-Back training, on recently diagnosed dementia patients, if you've already made the decision that cognitive training is worth pursui…

Hearsay and anecdote are not useful for determining the empirical validity of a theory or therapy. I don't know you, and I have no idea if your reporting is accurate, or if so, who this neurologist might have been, or whether they are trustworthy, and even if they are, I don't have any information as to whether this specific opinion is sound. Without empirical evidence, there is no objective reason to believe any part of this claim.

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#97
post #19
post #8

Earlier quoted context omitted.

I got my genes sequenced recently and it turns out I have a mutant gene that predisposes me to Alzheimers - APOE e4. it's a cholesterol shuttling gene! Very important to keep low fat, it effects your entire body.

Which service did you use for gene sequencing?

23andme

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#98
post #70

Earlier quoted context omitted.

Comment was about the research reaching the news section of the NHS.

www.nhs.uk/news exists specifically to debunk false health claims (I'm tech lead for this site)

Thought this was a great site. Then I looked for the rss feed. Still good but...

Re: Puzzle-solving 'doesn't slow down mental decline in older people'

#100
post #8

Earlier quoted context omitted.

I got my genes sequenced recently and it turns out I have a mutant gene that predisposes me to Alzheimers - APOE e4. it's a cholesterol shuttling gene! Very important to keep low fat, it effects your entire body.

I hadn’t heard that body fat composition affected Alzheimer’s risk. Out of curiosity, do you have a reference?

Alzheimer's is starting to be referred to as Type 3 diabetes that the correlation between metabolic syndrome and the disease is incredibly high.

I wonder how much this has to do with the relative uptake of carbohydrate sources and in particular refined sugars (namely fructose) in the typical diet. It seems the more that we learn, the less good refined vegetable oils and the level of fructose intake in people's diets is. I'm not convinced the amount of refined grains people eat is particularly good either.

However is seems that sugar (fructose specifically) and refined oils (linoleic acid specifically) are particularly bad in the increased quantities since the early 1900's.

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