Earlier quoted context omitted.
LSD doesn't have CIA origins, it's effects were discovered accidentally by Albert Hoffman. The CIA later commandeered research around LSD in order to look into how it could help train military personnel and also potentially be used as a weapon (while also stopping the research that was being done on its usefulness for therapy and creative problem solving). LSD is indeed more potent than some naturally occuring psyche…
I wasn't saying the CIA was it's discoverer, but rather it is the one that pushed LSD as part of the counter-culture movement of the 60's, which included experimentation on people (often without them knowing) in mkultra/artichoke programs and more. A quote from Timothy Leary: "I give the CIA total credit for sponsoring and initiating the entire conciousness movemenet, counter-culture events of the 1960's." As for why…
This is why synthetic perfumes are so extraordinarily dangerous for people with asthma, and cause several times as many deaths each year in Isreal as terrorism does, but natural scents are almost always fine. (It is possible to have dangerous allergic reactions to natural scents, too, causing severe edema and death, but this is far more rare.) Only tobacco is close to the same level of risk for asthmatics.
Of course, other forms of contamination are also possible, not to mention that other chemicals in the natural plant may be modifying the effect or compensating for side effects.