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Ibuprofen alters human testicular physiology

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91–100 of 216 posts

Re: Ibuprofen alters human testicular physiology

#92
post #26

At 1200mg/d, I feel like destroying your reproductive system would be the least of your concerns.

I've been prescribed up to 2400mg/d for a few weeks to deal with my knee. Not for the painkilling aspect (Because it wasn't painful), but for the anti-inflammatory.

Same with me, for a pinched nerve. Both for pain and anti-inflammatory.

Re: Ibuprofen alters human testicular physiology

#93
post #71

At 1200mg/d, I feel like destroying your reproductive system would be the least of your concerns.

Is the /d per day? If so that's well within what I've seen "normal" people take. A regular Advil is 200mg. The usual dose is two pills, so 400mg. If your larger it's common to take three or four pills. Multiply by a dose ever six hours and it's quite easy to get to 3200mg per day.

A regular dose in the United States is 200mg. In other countries, Spain for instance, you may see up to 800mg over the counter.

Re: Ibuprofen alters human testicular physiology

#94

Earlier quoted context omitted.

> It might even explain why so many cultures had rites to male adulthood involving extreme pain. Right. And a notable trend among those cultures is that they are all nearly extinct. So much for their fertility. Of course this observation could biased due to my own ignorance. I only remember, like, 3 such cultures, and they were your typical African/Amazonian/Aboriginal tribes that still live in near-neolithic conditi…

Fertility is only one aspect of evolutionary fitness.

Not sure why the downvotes, this is true.

Re: Ibuprofen alters human testicular physiology

#95
post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

> It might even explain why so many cultures had rites to male adulthood involving extreme pain. Right. And a notable trend among those cultures is that they are all nearly extinct. So much for their fertility. Of course this observation could biased due to my own ignorance. I only remember, like, 3 such cultures, and they were your typical African/Amazonian/Aboriginal tribes that still live in near-neolithic conditi…

Your comment is needlessly dismissive, and to be honest, just incorrect.

The cultures that are dominant today aren't dominant due to mere reproductive success. Ironically, fertility is low in almost all developed nations.

Re: Ibuprofen alters human testicular physiology

#96

Earlier quoted context omitted.

That is actually the dose I use for my lower back pain and inflammation when it flares up - for a couple of days perhaps once or twice a year. Dates from a slipped disc about 20 years ago. Never serious enough for surgery, but still unpleasant.

Have you tried dropping the dose and interleaving with acetomenophin? I have been hearing recently that's an increasingly popular strategy, sharing the load between the kidneys and liver.

Because they work in different ways, that's what I'm fond of doing for myself and my children. Start with ibuprofen, then try a table of acetaminophen a couple of hours later.

If it's a really bad headache, start with one of each.

Re: Ibuprofen alters human testicular physiology

#97
post #62
post #16

Earlier quoted context omitted.

some people can't handle the effect on the stomach. but if you can handle it, it's a good choice. Or marijuana

Marijuana kills your short term memory.

the low/no-thc high-cbd strains generally don’t do this.

Re: Ibuprofen alters human testicular physiology

#98
post #71

At 1200mg/d, I feel like destroying your reproductive system would be the least of your concerns.

Is the /d per day? If so that's well within what I've seen "normal" people take. A regular Advil is 200mg. The usual dose is two pills, so 400mg. If your larger it's common to take three or four pills. Multiply by a dose ever six hours and it's quite easy to get to 3200mg per day.

[deleted]

Re: Ibuprofen alters human testicular physiology

#99

At 1200mg/d, I feel like destroying your reproductive system would be the least of your concerns.

I've had two doctors suggest taking over 2000mg a day like it was nothing. One of them was a fellow hiker on the Appalachian Trail and suggested it as a daily regimen for regular joint pain (common for long-distance hikers). The other suggested it for aiding recovery from mild frostnip. (In both cases, I ended up only taking it for a few days.)

Unless you have stomach problems—NSAIDs are linked to ulcers—high doses of ibuprofen have not been thought of as terribly risky.

Re: Ibuprofen alters human testicular physiology

#100
post #28

Earlier quoted context omitted.

I tend to use naproxen but something tells me that would kill me as well

I think that all NSAIDs (like naproxen and ibuprofen) chew holes through your stomach lining, and a whole class of them were yanked from the market for causing heart attacks[1]. (But, yeah, naproxen seems to be one of the safest ones...) [1] https://en.wikipedia.org/wiki/COX-2_inhibitor

That study also raised concerns about older NSAIDs (including aspirin, acetaminophen and ibuprofen):

http://circ.ahajournals.org/content/115/12/1634

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