There have been at least 3 previous solutions for AD in mice which have never panned out in humans.
Source?
Chemical clears Alzheimer's protein and restores memory in mice
91–100 of 144 posts
Re: Chemical clears Alzheimer's protein and restores memory in mice
#92Earlier quoted context omitted.
Taking chemicals which haven't been made for human consumption and haven't been tested thoroughly could render you dead much faster than that.
Dead can to be honest be better than full blown Alzheimer's.
This. If there's a 10% chance it works and you don't die, I bet a lot of Alzheimer's patients would jump on it.
Re: Chemical clears Alzheimer's protein and restores memory in mice
#93Earlier quoted context omitted.
This seems like a pretty unfair generalization of Koreans. Assuming all scientists have the same shameful characteristics of a few doesn't seem very scientific, does it?
I think it's more of a generalization of the Korean scientific community, of which most Koreans are not a part.
It is an unfair generalisation in both cases. The wiki list of scientific fraud examples is very heavy on US examples.
Re: Chemical clears Alzheimer's protein and restores memory in mice
#94Earlier quoted context omitted.
Pretty sure Alzheimer's isn't good for you, either. I'd take any health risks over dementia, personally, and I'm sure most would, too. Looking forward to the FDA blocking this on "safety" grounds.
It's amazing to me that people are willing to experiment with an unapproved chemical that provides no proven benefit in humans, yet aren't willing to use human-proven therapies with known benefits such as statins.
The Cochrane report on statins confirms your claim:
http://www.cochrane.org/CD004816/VASC_statins-for-the-primar...
Re: Chemical clears Alzheimer's protein and restores memory in mice
#95Earlier quoted context omitted.
Pretty sure Alzheimer's isn't good for you, either. I'd take any health risks over dementia, personally, and I'm sure most would, too. Looking forward to the FDA blocking this on "safety" grounds.
It's amazing to me that people are willing to experiment with an unapproved chemical that provides no proven benefit in humans, yet aren't willing to use human-proven therapies with known benefits such as statins.
I think what you're responding to is NOT about willingness to experiment with unproven drugs, but rather a feeling of horror about dementia and Alzheimer's disease. These are awful afflictions that impact not just the victims but also their families.
That said, regardless of whether or not they're proven/approved/tested, drugs are never magic bullets. The ones used to treat the most serious chronic diseases always come with serious risks and profound side-effects. I don't expect that to change anytime soon.
Re: Chemical clears Alzheimer's protein and restores memory in mice
#96Earlier quoted context omitted.
Pretty sure Alzheimer's isn't good for you, either. I'd take any health risks over dementia, personally, and I'm sure most would, too. Looking forward to the FDA blocking this on "safety" grounds.
It's amazing to me that people are willing to experiment with an unapproved chemical that provides no proven benefit in humans, yet aren't willing to use human-proven therapies with known benefits such as statins.
I expect there is a Venn diagram that would cover this small subset of people that fulfill your 2 requirements but most people probably fall into one or the other.
Re: Chemical clears Alzheimer's protein and restores memory in mice
#97Re: Chemical clears Alzheimer's protein and restores memory in mice
#98Earlier quoted context omitted.
It's amazing to me that people are willing to experiment with an unapproved chemical that provides no proven benefit in humans, yet aren't willing to use human-proven therapies with known benefits such as statins.
Presumably these "people" you speak of are actually different people (unless you have evidence of the parent choosing not to use statins?) People tend to vary wildly in choices and opinions. Who knew!?
>> People tend to vary wildly in choices and opinions. Who knew!?
But some people think their choice or opinion is somehow the "correct" one and should be imposed on everyone ;-)
Re: Chemical clears Alzheimer's protein and restores memory in mice
#99This is heartening news; if not a cure, at least it suggests a promising avenue for future research into this terrible condition. This LiveScience[1] article is an easily read summary that also mentions a critique of the approach. Given the unfortunate history[2][3] of falsified Korean scientific research, it would be prudent to withhold judgment until these results have been reproduced in other labs around the world…
Wow, talk about cherry-picking. And those both resulted in jail time. How about the "unfortunate history" of falsified research in other countries? https://en.wikipedia.org/wiki/Scientific_misconduct#Notable_... Do you feel the same way about US scientific research?
If the research misconducts are from Japan, China and South Korean, they would immediately become the top news in the major media in USA. If they are from Western countries, well, most of them didn't even get mentioned in the same media. That is how unbiased these media are.
BTW, I am not even talking about Fox News and alike. NYT, you are in the list. The journalistic integrity of your articles has been dropping like a rock.
Re: Chemical clears Alzheimer's protein and restores memory in mice
#100it's a great day for mouse health
Relevant West Wing dialog: MARGARET Let me ask you this...Red meat has been found to cause cancer in white rats. Maraschino cherries have been found to cause cancer in white rats. Cellular phones have been found to cause cancer in white rats. Has anyone examined the possibility that cancer might be hereditary in white rats? DR. GRIFFITH Let me tell you something, I'm not 100% sure we've ruled that out.
Reminds me of a lecturer I had in a neuroscience class that informed us that "no one really checked whether all neurons had the same constants as the ones from the giant squid, but just assumed they did" (or something similar). Apparently anyone who thought of it assumed that something so blindingly obvious would already have been examined by someone else. It took decades before the error was found.