Earlier quoted context omitted.
"Make sure you've turned up the file descriptors" is the single-process socket server equivalent of "Turn off HTTP KeepAlive" for Apache sites. :) (Yeah, I've had outage because of this too.)
Surely you meant "Turn on HTTP pipelining"? Or is there something wrong with Apache's pipelining implementation?
Edit: Here's a FF discussion on it: https://bugzilla.mozilla.org/show_bug.cgi?id=264354 -