A lot of software in this space, for instance, has a fixed MAC address requirement for their license servers, and you report/pay depending on the number of cores. Whilst you can get around that sometimes, it would certainly void agreements and wouldn't hold up in an audit.
In some companies I've worked, this could drastically reduce the capital costs for engineers needing overpowered workstations that are analogous to Ferraris you only take out on weekends.
*who are already using AWS in other parts of their infrastructure.