Love this forecasting methodology
How long til we're all on Ozempic?
891–900 of 1001 posts
Re: How long til we're all on Ozempic?
#892Earlier quoted context omitted.
"Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse?" I think it is because if 90% of the population did half of what you do (and kudos for you for doing it), they wouldn't have a problem with weight, you just happen to be one of the unlucky few where it doesn't work and these drugs are useful.
Commenter: This drug helped me with weight loss. Commenter 2: Kodus to you. Let me just discount your anecdote as being unlucky and keep my current belief. But again, kudos. HN threads on weightloss are an utter waste of time.
I don't think that's particularly charitable, GGP said themselves that their issue is volume, that they're doing well in many other ways. GP is saying if everyone could do what they've done, many fewer would have the problem, and so maybe it would have less stigma.
Re: How long til we're all on Ozempic?
#893Earlier quoted context omitted.
The willpower frame actually works pretty well for a lot of people. If not than in our society almost everybody would be obese. This pill will make things worse for the group that hangs out in the treadmills and drinks green and disgusting smoothies. On topic, very happy this medicine exists, but let's pray god will keep the prescription only for BMI > 35.
> If not than in our society almost everybody would be obese. Isn't that already the case. I'm of belief, the failing isn't individual but societal. You have obese toddlers and wild animals in the US. I don't think this is a failure of willpower, it's a failure to investigate the actual causes of the obesity epidemic. Maybe it's sugar, perhaps it's highly processed oils, etc. Whatever it is, people aren't investigati…
I live in lala land. Obese children are rare, however overweight is 11% and declining from 15% post covid.
The school where my kids go to has zero obese and zero overweight kids (n = 300).
We have Starbucks, McDonalds, Dunkin' Donuts and the same brands like Heinz and Coca Cola. Pizza.
So, I am optimistic willpower can prevent us from a new Ozempic disorder. I suggest to go for willpower and not pills. If willpowers falls short, in my country when a child becomes obese, child welfare steps in. So let the government intervene (yep, you will lose your parental power) with a lifestyle program.
Re: How long til we're all on Ozempic?
#894Okay, how I found out about berberine being over the counter...this medical article and study
https://pubmed.ncbi.nlm.nih.gov/34981502/
Imagine only spending $11 with no side effects to spending $300 and up with major side effects.....
Re: How long til we're all on Ozempic?
#895One trend I noticed, whenever this topic is discussed in public forums, it attracts a lot of negativity from "just exercise and eat less" crowd (generalizing here). I wonder why it caused so much negative reaction? On the surface it shouldn't matter much, since it does not appear to harm ones who found a way to maintain healthy body without drugs. Yet it reliably causes a quite noticable number of folks to be quite aggressive towards either people using these drugs or companies making these. (Similar trend can be seen in other drugs like THC for example)?
Re: How long til we're all on Ozempic?
#896Earlier quoted context omitted.
For me, personally, it's that we don't really know the long term effects of these drugs ie are you actually "healthier". But we do know that diet and exercise work.
> But we do know that diet and exercise work. Sure - if you ignore the incredibly poor % of people who comply with a prescription of diet and exercise. If you include compliance then the drugs are way way way ahead.
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Re: How long til we're all on Ozempic?
#897I'd think it more likely that it'll be one of the next generation drugs, but I do agree with the premise that it will be really common. A few weeks ago I started a low dose of tirzepatide (aka Mounjaro, aka Zepbound) and the side effects are interesting. The biggest negative, which just takes adjustment, is drastically lower stomach capacity. Used to be that two eggs and two pieces of toast was breakfast. Now I bette…
> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…
All this study really shows is an analysis of medical records with no background of the peoples' diet or lifestyle. The outcome should be obvious and expected, those who are overweight and obese were found to stay that way.
The fact that the rate of obesity in the US has pretty consistently risen for decades makes that clear, you don't need statistical models of medical records to know that the rate of obesity could only really keep going up if those already obese stay that way.
Re: How long til we're all on Ozempic?
#898I've been on tirzepatide (Mounjaro) for 4 months now. I'm down 13% of my body weight. I realized that frequent cannabis consumption interferes with the weight loss, so I've kicked the habit from daily to occasionally on weekends. I've started walking 2-3 miles a day, 2-3 days a week regularly, in addition to eating less and being more motivated to calorie count. All this to say, this drug has been life changing for m…
In the future, this would be indistinguishable from an ad.
Re: How long til we're all on Ozempic?
#899Earlier quoted context omitted.
Commenter: This drug helped me with weight loss. Commenter 2: Kodus to you. Let me just discount your anecdote as being unlucky and keep my current belief. But again, kudos. HN threads on weightloss are an utter waste of time.
I don't think that's particularly charitable, GGP said themselves that their issue is volume, that they're doing well in many other ways. GP is saying if everyone could do what they've done, many fewer would have the problem, and so maybe it would have less stigma.
> I don't think that's particularly charitable,
As a direct reply to the challenge that the original poster made:
> > Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse?
They said nah, you were unlucky. In other words just dismiss his point outright.
Is that still uncharitable? Then so be it.
> GGP said themselves that their issue is volume, that they're doing well in many other ways.
Yes they said that they have a food addiction.
- The alcoholic said that his problem is the volume of alcohol intake
- The smoker said that…
Then asked why we won’t help food addicts. Just waffle on about self-discipline or hint at it.
This question is still yet to be answered.
> GP is saying if everyone could do what they've done, many fewer would have the problem, and so maybe it would have less stigma.
Maybe if those people had more self-discipline. Then maybe there would be less of a stigma.
You’re using the rationalized stigma to explain the stigma. This is at best circular.
Maybe we would respect ex-smokers more if they had the discpline to not ingest nicotine gum.
Re: How long til we're all on Ozempic?
#900Earlier quoted context omitted.
> One thing that it seems we are just starting to talk about with these drugs is the associated muscle and bone density loss. Muscle loss is associated with _any_ kind of weight loss. And GLP-1 drugs _improve_ the bone density: https://academic.oup.com/jcem/article/100/8/2909/2836097 It's likely simply because thinner people naturally move more.
Can these negative effects be countered/offset by continuing weight training? I lift 2-4 days a week.
Yes, but you would certainly still see some - it's just a consequence of weight loss. Even IFBB bodybuilders on god knows how many steroids see some muscle loss when cutting.
Eat a whole lot of protein, lift, and you're going to be doing more than fine in the muscle loss department.