Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Omicron variant more resistant to vaccine but causes less severe Covid: study

washingtonpost.com

Post reply on HN
Print view View original

821–830 of 1001 posts

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#821

Post by nikolay »

johnisgood wrote: post #788
exegete wrote: post #787

Earlier quoted context omitted.

mRNA vaccines have been a thing in labs for a few decades and first human clinical trials against a pathogen in 2013 https://en.m.wikipedia.org/wiki/MRNA_vaccine

> Before 2020, no mRNA technology platform (drug or vaccine) had been authorized for use in humans, so there was a risk of unknown effects.[79] The 2020 COVID-19 pandemic required faster production capability of mRNA vaccines, made them attractive to national health organisations, and led to debate about the type of initial authorization mRNA vaccines should get (including emergency use authorization or expanded acce…

No vaccine would have been authorized on billions of people before 2020 if it had such prevalent incidence of peri- and myocarditis! But now it's authorized even of toddlers, which have even higher chance for future heart issues! And all this, because politicians didn't have the balls to keep the face mask mandates!

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#822

Post by marderfarker2 »

d3ad1ysp0rk wrote: post #760
kyleblarson wrote: post #729

Earlier quoted context omitted.

Moderna CEO equity sales for the last couple years. Nothing to see here, no reason to distrust them pushing endless boosters: https://finance.yahoo.com/screener/insider/BANCEL%20STEPHANE...

I scrolled thru the last 2 years, and honestly I'm not sure what point you're trying to make. Too much profit? Sure. I don't think the boosters are going to be what solidifies that issue for corporations though.. Some timing issue with selling? I don't see it.

Pharma probably learnt what worked for software: turn perpetual licenses into subscriptions.

Chances are these “boosters” will become a quarterly occurrence, even when the virus pose little to no threat (to an already vaccinated person)

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#823

Post by deelowe »

s1artibartfast wrote: post #743
deelowe wrote: post #717

Earlier quoted context omitted.

Part of the approval process is ensuring there’s enough supply to support the intended use and, if there’s not enough, do a limited approval. That’s likely what’s going on here.

If you mean supply the population, this is not correct

My understanding is that the FDA is considering limited authorization in cases where there's not enough to cover all individuals.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#824

Post by x86_64Ubuntu »

marderfarker2 wrote: post #822
d3ad1ysp0rk wrote: post #760

Earlier quoted context omitted.

I scrolled thru the last 2 years, and honestly I'm not sure what point you're trying to make. Too much profit? Sure. I don't think the boosters are going to be what solidifies that issue for corporations though.. Some timing issue with selling? I don't see it.

Pharma probably learnt what worked for software: turn perpetual licenses into subscriptions. Chances are these “boosters” will become a quarterly occurrence, even when the virus pose little to no threat (to an already vaccinated person)

You mean like the flu virus? For which doctors say that we should get every year?

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#825

Post by landemva »

rbartelme wrote: post #556

"Less severe" as in less hospitalizations and death. The long-term effects of comorbidities are still being hashed out. A fair amount of the literature surrounding pulmonary megakaryocytes, platelets, and covid, is pretty alarming.

Not sure if I agree with this, 'The long-term effects of comorbidities are still being hashed out.'

I thought there was scientific consensus that being overweight is detrimental to health.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#826

Post by dfabulich »

Wowfunhappy wrote: post #778
dfabulich wrote: post #768

Earlier quoted context omitted.

I see why you're saying that, but I think you missed their point. Challenge trials might well allow us to make a safe vaccine available sooner to those who want it, but if we mandate a vaccine that has only undergone challenge trials and then that vaccine kills someone, it would certainly be politically disastrous for challenge trials.

Challenge trials are dangerous for the people who participate in the trials, but they aren’t any less rigorous.

I agree! But it would still be a political disaster if something does go wrong.

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#827

Post by marco_yolo »

starik36 wrote: post #755
liber8 wrote: post #679

Earlier quoted context omitted.

According to reports, the original BioNTech vaccine was developed in a matter of hours: https://www.businessinsider.com/pfizer-biontech-vaccine-desi... Moderna's was done in two days.

Right, but the underlying tech was in development for a decade or more. I can deploy an app to Azure, tell it to allocate a server farm, databases, Redis, queues, etc... in 5 minutes too. But that's only because someone took years to do all the necessary work.

why would you deploy an app to azure?

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#828

Post by tekknik »

Animats wrote: post #676

Moderna is working on a vaccine targeting the Omicron variant for 2022.[1] The mRNA vaccine technology is "agile". There's a workflow from sequencing a virus to generating a candidate vaccine. It only took two days to generate the original COVID-19 vaccine. It's the clinical testing in small, then large groups that's the time consuming part. Also, the inhaled vaccines are entering clinical testing.[2] It's not like w…

Yay, more injections of experimental vaccines!

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#829

Post by renaudg »

renaudg wrote: post #370
roody15 wrote: post #175

This is honesty good news. The best case scenario is a new less deadly highly contagious strain that become the most dominant and spreads worldwide. Way too many comments and articles that try and keep the fear train running full steam. A mild strain of covid that is contagious, leads to natural immunity and doesn’t require a vaccine is an absolute win win for the world.

> The best case scenario is a new less deadly highly contagious strain that become the most dominant and spreads worldwide. No, this scenario wouldn't be good news at all. Firstly, a marginally lower case fatality rate is a linear improvement, whereas much higher transmissibility is an exponential worsening. In other words, the reduced risk of an infected person getting into hospital is dwarfed by the exponential inc…

Good explanation of why a milder more contagious variant is bad news : https://twitter.com/AdamJKucharski/status/134356742510788198...

Re: Omicron variant more resistant to vaccine but causes less severe Covid: study

#830

Post by erik_seaberg »

stnmtn wrote: post #535
bagacrap wrote: post #534

Earlier quoted context omitted.

there really can't be an "exponential" increase in the number of cases, whatever that means, given that there's a hard upper bound which is the number of hosts.

While technically correct, you and I both know what they meant by exponential. Sure, there's a limit, but if we're looking at function that is exponential until it reaches an inflection point where there's simply less hosts to infect than possible...

That is the https://en.wikipedia.org/wiki/Logistic_function, which is pretty close to exponential growth followed by logarithmic saturation.
Post reply on HN