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Bird flu viruses are resistant to fever, making them a major threat to humans

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Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#81

Earlier quoted context omitted.

Bread is an ultra-processed food.

Care to engage more substantially than this, or are you just repeating the argument that because UPF is imperfectly defined, that means UPF as a category is absolutely worthless and therefore we should dismiss all precautionary options surrounding any and all UPFs with prejudice?

UPF as a category is absolutely worthless. What matters is the contents and effects, not the process used to get there.

https://peterattiamd.com/davidallison3/

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#82
post #38

Earlier quoted context omitted.

I can't speak for OP, they may have been advocating for giving up farming animals (or fowl) altogether, but personally I see a huge inflection point between traditional and factory farming methods with regards to the level of risk. When you are compromising the immunity of your livestock, you beg trouble. I understand the temptation to zoom out to a several hundred year timespan, that can be clarifying. But when (as…

Consider how many fewer people interact with livestock now than before factory farms. I don't know if it matters but there are significantly fewer farmers than there used to be by several orders of magnitude. Also, before cars, the streets of major cities were covered in horse shit.

[deleted]

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#83

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

Fever helps against all kinds of illnesses but it can also be deadly, so having fever reducting medicine around is a smart precaution IMO. If you're otherwise healthy and are dealing with a mild seasonal infection and have got something important going on, I can see why people would choose to reduce symptoms at the cost of taking longer to recover. Lots of people go overboard with this, though, like taking flu reduct…

> like taking flu reduction medicine with every single cold or using medication to go to work sick.

Basically how I grew up. I took painkillers and throat lozenges in my backpack to school.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#84

[flagged]

Why we keep killing the birds that survive the infection is beyond me. It's an evolutionary pressure that we refuse to allow to work. It's almost as if we want to give the flu as many opportunities as possible to spill over, instead of just letting the birds who have immunity survive and thus basically drive the virus to extinction.

The main idea behind culling is to prevent the virus itself from evolving inside the herd. Viruses evolve much more rapidly than birds.

Now sure, if there were a clear way to tell that some birds have been infected and survived and recovered, it could be a good idea not to sacrifice those birds, and even to specifically breed them. However, there is no good way to do so, especially not with any confidence. It's much more likely you'll end up infecting any population that you put these new birds in to.

So, the best and cheapest solution is to sacrifice the entire group, to prevent the disease from spreading to other populations, and to do so quickly, to prevent the virus from evolving or crossing a species boundary.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#85
post #83

Earlier quoted context omitted.

Fever helps against all kinds of illnesses but it can also be deadly, so having fever reducting medicine around is a smart precaution IMO. If you're otherwise healthy and are dealing with a mild seasonal infection and have got something important going on, I can see why people would choose to reduce symptoms at the cost of taking longer to recover. Lots of people go overboard with this, though, like taking flu reduct…

> like taking flu reduction medicine with every single cold or using medication to go to work sick. Basically how I grew up. I took painkillers and throat lozenges in my backpack to school.

Due to a condition I was born with, I was raised the opposite. No over the counter medication my entire life, with some exceptions. I usually decline pain management in ER, for things like broken bones, but for surgeries and stuff of course I have no choice as I go under.

I will take what the doctor orders though, to treat illness and conditions though thankfully at this stage there hasn't been many instances. Usually that's antibiotics.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#86
post #72

Well, most humans (unlike me) take Tylenol even with a "fever" of just 38°C/100.5°F, so what difference does it make?

Unlike us, the virus will replicate much more quickly in their bodies. It wont kill them, but will likely make the infection last longer.

Havent had a fever in many years, since taking flu and covid shots each year.

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#89

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

It may go further than that:

> Fever is used by organisms as diverse as fish, amphibians, reptiles and mammals (see for reference Basu and Srivastava, 2003). Since fever is metabolically expensive, it must provide substantial advantage to the host. Surprisingly little is known about immunological effects mediated by fever, a lack of understanding that might be attributable in part to the common ignorance in clinical practice with respect to benefits fever might provide. Post-operative infections can be prolong survival: patients developing empyema after lung cancer surgery have improved 5-year survival (50% (n = 18) vs 22% (n = 411)) (Ruckdeschel et al, 1972). In this light, it seems unfortunate that fever is usually suppressed in hospital routine.

> The phenomenon of spontaneous regression and remission from cancer has been observed by many physicians and was described in hundreds of publications. However, suggestive clues on cause or trigger are sparse and not substantiated by much experimental evidence. [...] At least in a larger fraction of cases a hefty feverish infection is linked with spontaneous regression in time and is investigated as putative trigger.

> Professor Busch in 1868 introduced the infection of cancer patients by purpose as a novel strategy to treat cancer. He achieved a dramatic regression with his first patient using live Streptococcus pyogenes bacteria, the pathogen leading to erysipelas, published in the German Journal ‘Berliner Klinische Wochenschrift’ (Busch, 1868). Beginning in 1891, this strategy was exploited by Coley, who had some reading knowledge of German (Hall, 1998). Coley systematically applied Streptococcus pyogenes extracts – later called ‘Coley’s toxin’ – to cancer patients and achieved a remarkable rate of regressions. A retrospective compilation of cases considered inoperable at the time of treatment between 1891 and 1936, which was conducted by Wiemann and Starnes (1994, Table 2), determined a remission rate of 64% (108/170) and a 5-year survival rate of larger than 44%. Coley used to inject his extract once or twice a week over a period ranging from a few weeks to several months. His method became quite famous and was tested on hundreds of patients by him and contemporary physicians, but overshadowed by the development of X-ray treatment which was regarded to be much more powerful and of broader applicability.

> Since cancer is usually a slowly progressing disease with occasionally long periods of dormancy, putative beneficial fever effects should also precipitate as preventive efficacy. This can indeed be found. In a cohort of 603 melanoma patients compared to 627 population controls, an inverse correlation was found between melanoma risk and number of recorded infections on the one hand and between melanoma risk and fever height on the other hand, leading to a combined reduction of melanoma risk of about 40% for people with a history of three or more infections with high fever above 38.51C (Koelmel et al, 1999). Mastrangelo et al (1998) report a striking inverse correlation between the number of infections and mortality from tumours in Italy in the period 1890 –1960: every 2% reduction in the number of infectious diseases was followed by a 2% increase in tumours about 10 years later.

https://www.nature.com/articles/6602386.pdf

https://pubmed.ncbi.nlm.nih.gov/16444847/

Re: Bird flu viruses are resistant to fever, making them a major threat to humans

#90

Huh. I don’t know if I’m picking up what they’re putting down here, but it kind of sounds like suppressing fever e.g. with Tylenol would actually be bad for (normal) flu progression.

It is, as others have pointed out.

Although, we’re very unusual humans in the grand scheme of things. So using medication might be reasonable. The brain might start taking damage around 104F. That was probably a good tradeoff for a peasant farmer (our ancestors, on average). Most of us nowadays just think for a living, not such a good tradeoff for us. Take the fever suppressant, what’s the worst that’ll happen if you miss an extra day of work?

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