I did my Ph. D. between 1998 and 2003. I did not regret doing that but after one year as a post doc I left the academic world for one simple reason: I realized the career paths were limited to two options I did not like: option 1) try to shoot for a tenure position somewhere via a long series of post doc positions. Expect to be mostly busy managing postdocs and researchers and lobbying for funding by the time you get…
My fear of going the startup route is that it ends up more like being a PI and having to chase funding and so much of the success lies less in the tech and more in the execution of how you sell it.
So go for funding and get the money to hire a team to do the fun stuff or do the fun stuff yourself on the side…