Earlier quoted context omitted.
I think that 50k/1% should be considered only as a 'hobby occupation'. Or, if one is trying to change a field of work. Because this early employee 1% is a) going to get diluted; b) it is over 4 years; c) most likely will result in $0 - $5000 cash-wise. And 50k (without benefits I assume) is.. well nothing.
If you're already well-off enough to not need income, or have a rich doctor as a spouse, it's quite reasonable to trade salary for equity. Also, I'd love to take $50k/yr + 1% equity in an already successful startup. Say, Facebook.
It is never reasonable to trade your skills at substantially below-market compensation - regardless of if you can afford to do so. I have a lot of savings, but that doesn't make it reasonable for me to start lighting cigars with $20 bills.
Equity is a form of compensation, in this case dchichkov worked it out to be a expected value of $5K (or thereabouts) - how does one justify taking a haircut substantially more than this? (in this case, the haircut is on the order of $50-100K depending on the person).